1088704-78-2
1088704-78-2
Chemical Structure
DHFR-IN-24
- CAS No.: 1088704-78-2
- Formula:C22H21IN2S2
- Molecular Weight:504.45
InChIKey: YMPALAHOKDLRPX-UHFFFAOYSA-M
SMILES: CN(C1=CC=C(C=C1)C2=CC=C(S2)/C=C/C3=[N+](C4=CC=CC=C4S3)C)C.[I-]
Biological Activity: DHFR-IN-24, a benzothiazole derivative, is a dihydrofolate reductase (DHFR) inhibitor. DHFR-IN-24 has intrinsic antibacterial activity against both Gram-positive and Gram-negative strains. DHFR-IN-24 synergistically combines DHFR inhibition with photodynamic therapy (PDT) for enhanced antibacterial activity against multidrug-resistant pathogens[1].
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DHFR-IN-24 | DHFR-IN-24, a benzothiazole derivative, is a dihydrofolate reductase (DHFR) inhibitor. DHFR-IN-24 has intrinsic antibacterial activity against both Gram-positive and Gram-negative strains. DHFR-IN-24 synergistically combines DHFR inhibition with photodynamic therapy (PDT) for enhanced antibacterial activity against multidrug-resistant pathogens. | |||||||||||||||||||||
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References
Keywords
