2636771-45-2
Chemical Structure
IZTZ-1
- CAS No.: 2636771-45-2
- Formula:C32H35N7S
- Molecular Weight:549.73
IUPAC Name: 2-(4,5-bis(4-(4-methylpiperazin-1-yl)phenyl)-1H-imidazol-2-yl)benzo[d]thiazole
InChIKey: GQVJPANFTBPXFF-UHFFFAOYSA-N
SMILES: CN1CCN(C2=CC=C(C3=C(C4=CC=C(N5CCN(C)CC5)C=C4)N=C(C6=NC7=CC=CC=C7S6)N3)C=C2)CC1
Biological Activity: IZTZ-1, an imidazole-benzothiazole conjugate, is a c-MYC G4 ligand. IZTZ-1 is able to downregulate the c-MYC expression by stabilizing c-MYC G4. IZTZ-1 induces cell cycle arrest, apoptosis, thereby inhibiting cell proliferation in B16 cells. IZTZ-1 shows antitumor activity, and can be used for melanoma research[1].
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IZTZ-1 | 99.47% | IZTZ-1, an imidazole-benzothiazole conjugate, is a c-MYC G4 ligand. IZTZ-1 is able to downregulate the c-MYC expression by stabilizing c-MYC G4. IZTZ-1 induces cell cycle arrest, apoptosis, thereby inhibiting cell proliferation in B16 cells. IZTZ-1 shows antitumor activity, and can be used for melanoma research. | ||||||||||||||||||||
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Keywords
