2 Results for "

CA IX-IN-3

" in MedChemExpress (MCE) Product Catalog:
Products (2)

2 Results for "CA IX-IN-3" in MCE Product Catalog:

Cat. No.: HY-168767
CAS No.: 333413-02-8
Target:  

Carbonic Anhydrase

Research Areas:  

Others

CA IX-IN-3 (Compound 27) is a selective and potent carbonic anhydrase IX (CA IX) inhibitor with an IC50 of 0.48 nM .
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Cat. No.: HY-178030
CAXII-IN-3 is an effective carbonic anhydrase (CA XII) inhibitor with a Ki of 53 nM. CAXII-IN-3 exhibits selective inhibition against multiple human CA subtypes with Kis of 5.3 μM, 75 nM, 1.9 μM, > 10 μM against CA I, CA II, CA IV and CA IX. CAXII-IN-3 mainly inhibits CA II and XII, and reduces aqueous humor production. CAXII-IN-3 exhibits β3-AR agonistic activity, can dilate retinal blood vessels, and improve optic nerve perfusion. CAXII-IN-3 can be used in the research of ocular disorders such as glaucoma .
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