1 Result for "

CDK2/FLT4/PDGFRA-IN-1

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "CDK2/FLT4/PDGFRA-IN-1" in MCE Product Catalog:

Cat. No.: HY-173124
Target:  

CDK VEGFR PDGFR Apoptosis

Research Areas:  

Cancer

CDK2/FLT4/PDGFRA-IN-1 (Compound 4a) is a potent inhibitor of CDK2/cyclin A, FLT4 (VEGFR3) and PDGFRA, with IC50s of 1.672, 0.554, and 0.629 μM, respectively. CDK2/FLT4/PDGFRA-IN-1 exhibits potent antiproliferative effects against cancer cells (lung EBC-1, pancreatic ductal adenocarcinoma AsPC-1, colorectal HT-29 cells). CDK2/FLT4/PDGFRA-IN-1 can also induce apoptosis in cancer cells [1].
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