CDK2/FLT4/PDGFRA-IN-1
CDK2/FLT4/PDGFRA-IN-1 (Compound 4a) is a potent inhibitor of CDK2/cyclin A, FLT4 (VEGFR3) and PDGFRA, with IC50s of 1.672, 0.554, and 0.629 μM, respectively. CDK2/FLT4/PDGFRA-IN-1 exhibits potent antiproliferative effects against cancer cells (lung EBC-1, pancreatic ductal adenocarcinoma AsPC-1, colorectal HT-29 cells). CDK2/FLT4/PDGFRA-IN-1 can also induce apoptosis in cancer cells.
For research use only. We do not sell to patients.
- Formula: C26H20N4O3
- Molecular Weight:436.46
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Biological Activity
Chemical Information
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Molecular Weight 436.46
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Formula C26H20N4O3
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SMILES
O=C1C(NC2=CC=C(OCC3=CN(CC4=CC=CC=C4)N=N3)C=C2)=CC(C5=C1C=CC=C5)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
CDK2/FLT4/PDGFRA-IN-1 Related Classifications
HY-173124 Related Classifications
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