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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
18 Results for "
CFI
" in MedChemExpress (MCE) Product Catalog:
Products (18)
18 Results for "CFI" in MCE Product Catalog:
7
7 Publications Verification
Synonyms: CFI-402257
CFI-402257 is a highly selective and orally bioavailable TTK/Mps1 inhibitor with an IC50 of 1.7 nM for TTK in vitro. CFI-402257 has anti-cancer activity .
7
7 Publications Verification
Synonyms: CFI-402257 hydrochloride
CFI-402257 hydrochloride is a highly selective and orally bioavailable TTK/Mps1 inhibitor with an IC50 of 1.7 nM for TTK in vitro. CFI-402257 hydrochloride has anti-cancer activity .
6
6 Cited Publications
Synonyms: CFI-400945 free base
Target:
Research Areas:
CFI-400945 free base is a potent, selective and orally bioavailable PLK4 inhibitor with a Ki and an IC50 of 0.26 nM and 2.8 nM, respectively.
6
6 Cited Publications
Synonyms: CFI-400945 fumarate
Target:
Research Areas:
CFI-400945 fumarate is a potent, selective and orally bioavailable PLK4 inhibitor with a Ki and an IC50 of 0.26 nM and 2.8 nM, respectively.
6
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Ocifisertib hydrochloride (CFI-400945 hydrochloride) is the hydrochloride salt form of Ocifisertib (HY-12300). Ocifisertib hydrochloride is an orally active PLK4 inhibitor with a Ki and an IC50 of 0.26 nM and 2.8 nM. Ocifisertib hydrochloride inhibits growth of various cancer cells, arrests cell cycles at G2/M phase, and induces apoptosis. Ocifisertib hydrochloride exhibits antitumor efficacy in mouse model .
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(1E)-CFI-400437 dihydrochloride is a potent PLK4 (IC50= 0.6 nM) inhibitor and selective against other members of the PLK family (>10 μM). (1E)-CFI-400437 dihydrochloride inhibits Aurora A, Aurora B, KDR and FLT-3 with IC50s of 0.37, 0.21, 0.48, and 0.18 μM, respectively. Antiproliferative activity .
Cat. No.: HY-123675
CAS No.: 1338793-07-9
CFI-400936 is a potent TTK inhibitor with an IC50 of 3.6 nM. CFI-400936 has antitumor activity .
Cat. No.: HY-120279A
CAS No.: 1169211-37-3
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Research Areas:
CFI-400437 is an indolinone-derived, ATP-competitive kinase inhibitor with high selectivity for PLK4 (IC50 of 0.6 nM) .
Cat. No.: HY-120032
CAS No.: 1610676-27-1
CFI-401980 is a selective tyrosine threonine kinase MPS1 inhibitor with a Ki of 0.8 nM. CFI-401980 inhibits the proliferation of HCT116 cell lines. CFI-401980 can be studied in anti-cancer research .
Cat. No.: HY-116190
CAS No.: 1430741-35-7
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Research Areas:
CFI-401870 is an orally active threonine tyrosine kinase (TTK (Mps1)) inhibitor with an IC50 of 3.1 nM. CFI-401870 exhibits IC50s against PLK4, KDR, AURKA and other kinases such as AURKB/INCENP were all greater than 1 μM.CFI-401870 inhibits the growth of various cancer cells, causing chromosome lag, an increase in aneuploidy and cell cycle arrest. CFI-401870 can be used for the study of cancers such as colon cancer .
Cat. No.: HY-RS02567
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CFI Human Pre-designed siRNA Set A contains three designed siRNAs for CFI gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-101340AR
CAS No.: 1610677-37-6
Synonyms: CFI-402257 hydrochloride (Standard)
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Research Areas:
Luvixasertib (hydrochloride) (Standard) is the analytical standard of Luvixasertib (hydrochloride) (HY-101340A). This product is intended for research and analytical applications. CFI-402257 hydrochloride is a highly selective and orally bioavailable TTK/Mps1 inhibitor with an IC50 of 1.7 nM for TTK in vitro. CFI-402257 hydrochloride has anti-cancer activity .
Cat. No.: HY-RS20677
Target:
Research Areas:
Cfi Mouse Pre-designed siRNA Set A contains three designed siRNAs for Cfi gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS27188
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Research Areas:
Cfi Rat Pre-designed siRNA Set A contains three designed siRNAs for Cfi gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-P703770
Purity: ≥ 90%, as determined by reducing SDS-PAGE.;≥ 90%, as determined by HPLC.
Synonyms: Complement factor I; C3B/C4B inactivator; CFI
Cat. No.: HY-P703793
Purity: ≥ 90%, as determined by Bis-Tris PAGE.
Synonyms: Complement factor I; C3B/C4B inactivator; CFI
Cat. No.: HY-P88426A
Synonyms: AHUS3; ARMD13; C3b-INA; C3BINA; FI; IF; KAF
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
