1610759-22-2
1610759-22-2
Chemical Structure
Luvixasertib
Synonym(s): CFI-402257
- CAS No.: 1610759-22-2
- Formula:C28H30N6O3
- Molecular Weight:498.58
IUPAC Name: N-cyclopropyl-4-(7-((((1s,3s)-3-hydroxy-3-methylcyclobutyl)methyl)amino)-5-(pyridin-3-yloxy)pyrazolo[1,5-a]pyrimidin-3-yl)-2-methylbenzamide
InChIKey: PMQUGSPFUBGJCZ-CHOKWEPUSA-N
SMILES: CC1=CC(C2=C3N=C(OC4=CN=CC=C4)C=C(NC[C@@H]5C[C@@](O)(C)C5)N3N=C2)=CC=C1C(NC6CC6)=O
Biological Activity: CFI-402257 is a highly selective and orally bioavailable TTK/Mps1 inhibitor with an IC50 of 1.7 nM for TTK in vitro. CFI-402257 has anti-cancer activity[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
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Luvixasertib | 99.9600% | CFI-402257 is a highly selective and orally bioavailable TTK/Mps1 inhibitor with an IC50 of 1.7 nM for TTK in vitro. CFI-402257 has anti-cancer activity. | ||||||||||||||||||||
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Structural Analogs
-
Similarity Score 0.99
HY-101340ALuvixasertib hydrochloride -
Similarity Score 0.64
HY-120032CFI-401980 -
Similarity Score 0.51
HY-12859BAY1217389 -
Similarity Score 0.48
HY-133551WF-47-JS03 -
Similarity Score 0.47
HY-171787PPA-037 -
Similarity Score 0.47
HY-12658Mps1-IN-4 -
Similarity Score 0.46
HY-110242Mps-BAY2a -
Similarity Score 0.46
HY-144399ACD33 splicing modulator 1 hydrochloride -
Similarity Score 0.46
HY-148075PI4KIIIbeta-IN-11 -
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