1169211-37-3
1169211-37-3
Chemical Structure
CFI-400437
- CAS No.: 1169211-37-3
- Formula:C29H28N6O2
- Molecular Weight:492.57
IUPAC Name: (E)-5-methoxy-3-((3-((E)-2-(6-(4-methylpiperazin-1-yl)pyridin-3-yl)vinyl)-1H-indazol-6-yl)methylene)indolin-2-one
InChIKey: GBUDRABUNBYJKG-WWAWLHJKSA-N
SMILES: O=C1NC2=C(C=C(OC)C=C2)/C1=C\C3=CC4=C(C=C3)C(/C=C/C5=CC=C(N6CCN(C)CC6)N=C5)=NN4
Biological Activity: CFI-400437 is an indolinone-derived, ATP-competitive kinase inhibitor with high selectivity for PLK4 (IC50 of 0.6 nM)[1].
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CFI-400437 | CFI-400437 is an indolinone-derived, ATP-competitive kinase inhibitor with high selectivity for PLK4 (IC50 of 0.6 nM). | |||||||||||||||||||||
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References
Keywords
