9 Results for "

CHRM1

" in MedChemExpress (MCE) Product Catalog:
Products (9)

9 Results for "CHRM1" in MCE Product Catalog:

12
12 Publications Verification
製品番号: HY-B0298
CAS 番号: 15686-51-8
別名: HS-592; Meclastine
Clemastine (HS-592; Meclastine) is an orally active, blood-brain barrier-permeable H1 histamine receptor (H1 histamine receptor) antagonist with potent antiallergic effects. Clemastine also antagonizes muscarinic acetylcholine receptors (mAChR), particularly the M1 and M4 subtypes. In addition to antihistamine effects, Clemastine exhibits multiple pharmacological activities, especially in promoting central nervous system remyelination, activating autophagy and pyroptosis, exerting anti-apoptotic and neuroprotective effects, and suppressing inflammation [1] .
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2
2 Cited Publications
製品番号: HY-N0735
CAS 番号: 104112-82-5
Phellodendrine chloride is an orally active plant alkaloid. Phellodendrine chloride inhibits the proliferation of KRAS-mutated pancreatic cancer cells by suppressing macropinocytosis and glutamine metabolism, inducing ROS accumulation and mitochondrial apoptosis. Phellodendrine chloride promotes autophagy by activating the AMPK/mTOR pathway, alleviating intestinal damage in ulcerative colitis. Phellodendrine chloride can alleviate gouty arthritis by inhibiting the IL-6/STAT3 signaling pathway. Phellodendrine chloride suppresses allergic reactions by altering the conformation of MRGPRB3/MRGPRX2 protein, thereby inhibiting the activation of PKC and subsequent downstream MAPK and NF-κB signaling. Phellodendrine chloride inhibits the AKT/NF-κB pathway and down-regulates the expression of COX-2, thereby protecting zebrafish embryos from oxidative stress. Phellodendrine chloride has an anti-major depressive disorder (MDD) effect by down-regulating CHRM1, HTR1A, and the PI3K/Akt signaling pathway [1] .
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製品番号: HY-N0427
CAS 番号: 6873-13-8
Phellodendrine is an orally active plant alkaloid. Phellodendrine inhibits the proliferation of KRAS-mutated pancreatic cancer cells by suppressing macropinocytosis and glutamine metabolism, inducing ROS accumulation and mitochondrial apoptosis. Phellodendrine promotes autophagy by activating the AMPK/mTOR pathway, alleviating intestinal damage in ulcerative colitis. Phellodendrine can alleviate gouty arthritis by inhibiting the IL-6/STAT3 signaling pathway. Phellodendrine suppresses allergic reactions by altering the conformation of MRGPRB3/MRGPRX2 protein, thereby inhibiting the activation of PKC and subsequent downstream MAPK and NF-κB signaling. Phellodendrine inhibits the AKT/NF-κB pathway and down-regulates the expression of COX-2, thereby protecting zebrafish embryos from oxidative stress. Phellodendrine has an anti-major depressive disorder (MDD) effect by down-regulating CHRM1, HTR1A, and the PI3K/Akt signaling pathway [1] .
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製品番号: HY-RS18169
研究分野:  

Others

Chrm1 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Chrm1 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

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製品番号: HY-RS02660
研究分野:  

Others

CHRM1 Human Pre-designed siRNA Set A contains three designed siRNAs for CHRM1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

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製品番号: HY-RS24643
研究分野:  

Others

Chrm1 Rat Pre-designed siRNA Set A contains three designed siRNAs for Chrm1 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.

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製品番号: HY-N0735R
CAS 番号: 104112-82-5
Phellodendrine chloride (Standard) is the analytical standard of Phellodendrine chloride (HY-N0735). Phellodendrine chloride is an orally active plant alkaloid. Phellodendrine chloride inhibits the proliferation of KRAS-mutated pancreatic cancer cells by suppressing macropinocytosis and glutamine metabolism, inducing ROS accumulation and mitochondrial apoptosis. Phellodendrine chloride promotes autophagy by activating the AMPK/mTOR pathway, alleviating intestinal damage in ulcerative colitis. Phellodendrine chloride can alleviate gouty arthritis by inhibiting the IL-6/STAT3 signaling pathway. Phellodendrine chloride suppresses allergic reactions by altering the conformation of MRGPRB3/MRGPRX2 protein, thereby inhibiting the activation of PKC and subsequent downstream MAPK and NF-κB signaling. Phellodendrine chloride inhibits the AKT/NF-κB pathway and down-regulates the expression of COX-2, thereby protecting zebrafish embryos from oxidative stress. Phellodendrine chloride has an anti-major depressive disorder (MDD) effect by down-regulating CHRM1, HTR1A, and the PI3K/Akt signaling pathway.
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製品番号: HY-P72138
純度:  ≥ 90%, as determined by reducing SDS-PAGE.
別名: CHRM1; CHRM-1Muscarinic acetylcholine receptor M1
Species:  
Rat
Source:  
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製品番号: HY-P703102
純度:  ≥ 85%, as determined by reducing SDS-PAGE.
別名: Muscarinic acetylcholine receptor M1; CHRM1; Homo sapiens; Human; G-protein coupled receptor; Receptor; Transducer
Species:  
Source:  
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