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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
7 Results for "
CXCR7/ACKR3
" in MedChemExpress (MCE) Product Catalog:
Products (7)
7 Results for "CXCR7/ACKR3" in MCE Product Catalog:
CCX-777 is an orthosteric binder and partial agonist of CXCR7/ACKR3. CCX-777 induces the recruitment of β-arrestin 2 and affects the rebinding of chemokines to ACKR3. CCX-777 functions to stabilize the ACKR3 receptor and promotes the formation of a monodisperse, stable complex of the receptor in DDM/CHS micelles. CCX-777 is widely used in cancer-related research [3] .
Cat. No.: HY-P10333A
Target:
Research Areas:
Cat. No.: HY-P10333
CAS No.: 2866266-58-0
Target:
Research Areas:
Cat. No.: HY-182533
CAS No.: 3035425-93-2
Target:
Research Areas:
LN5972 is a selective ACKR3 agonist with an EC50 of 3.40 μM, showing higher selectivity for ACKR3 over CXCR4. LN5972 induces β-arrestin recruitment to ACKR3/CXCR7. LN5972 reduces the surface expression of P-selectin. LN5972 is applicable to studies related to platelet-mediated thrombosis .
Cat. No.: HY-123813A
CCX-777 formic is an orthosteric binder and partial agonist of CXCR7/ACKR3. CCX-777 formic induces the recruitment of β-arrestin 2 and affects the rebinding of chemokines to ACKR3. CCX-777 formic functions to stabilize the ACKR3 receptor and promotes the formation of a monodisperse, stable complex of the receptor in DDM/CHS micelles. CCX-777 formic is widely used in cancer-related research [3] .
Cat. No.: HY-P700537
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: ACKR3; Chemokine (C-X-C Motif) Receptor 7; Prev. CMKOR1; G-Protein Coupled Receptor 159; Prev. CXCR7; CXC-R7; GPR159; CXCR-7; RDC1; RDC-1; Chemokine Orphan Receptor 1; G Protein-Coupled Receptor; G-Protein Coupled Receptor RDC1 Homolog; Atypical Chemokine
Species:
Human
Source:
E. coli
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
