2866266-58-0
2866266-58-0
Chemical Structure
LIH383
- CAS No.: 2866266-58-0
- Formula:C45H72N16O8S
- Molecular Weight:997.22
InChIKey: HKVZPBVWPFDBBQ-LBBUGJAGSA-N
SMILES: O=C(NCC(NCC(N[C@@H](CC1=CC=CC=C1)C(N[C@@H](CCSC)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CCCCN)C(N)=O)=O)=O)=O)=O)=O)=O)[C@H](CC2=CC=CC=C2)N
Biological Activity: LIH383 is an agonist of ACKR3 (CXCR7) (EC50=0.61 nM). LIH383 efficiently induces the recruitment of β-arrestin to ACKR3 but does not trigger typical G protein signaling[1].
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LIH383 | LIH383 is an agonist of ACKR3 (CXCR7) (EC50=0.61 nM). LIH383 efficiently induces the recruitment of β-arrestin to ACKR3 but does not trigger typical G protein signaling. | |||||||||||||||||||||
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