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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
13 Results for "
Ca2+ sensitivity
" in MedChemExpress (MCE) Product Catalog:
Products (13)
13 Results for "Ca2+ sensitivity" in MCE Product Catalog:
13
13 Publications Verification
Cat. No.: HY-D0716
CAS No.: 121714-22-5
Synonyms: Fluo-3-pentaacetoxymethyl ester
7
7 Cited Publications
Synonyms: R-568 hydrochloride; NPS R-568
Tecalcet Hydrochloride (R 568 Hydrochloride), an orally active calcimimetic compound, allosterically and positively modulates the calcium-sensing receptor (CaSR). Tecalcet Hydrochloride (R 568 Hydrochloride) increases the sensitivity to activation by extracellular Ca 2+ .
Cat. No.: HY-D0077
CAS No.: 195136-58-4
Synonyms: Oregon green 488
Target:
Research Areas:
2',7'-Difluorofluorescein (Oregon green 488) is a fluorescein derivative and a pH-sensitive fluorescent probe (pKa ~4.7). Upon excitation at 488 nm, 2',7'-Difluorofluorescein exhibits pH-sensitive fluorescence intensity through the formation of dianions, while its pH sensitivity decreases under excitation at 450 nm, allowing its use in ratiometric pH analysis. 2',7'-Difluorofluorescein can be used for the quantitative analysis of pH values in the range of 2-7 in submicron aerosol particles. 2',7'-Difluorofluorescein undergoes buffer-mediated and buffer-free excited-state proton transfer between different protonated forms, and its cationic form undergoes rapid excited-state deprotonation. 2',7'-Difluorofluorescein is resistant to photodegradation, maintains stable absorption and fluorescence properties within the physiological pH range, and serves as a fluorescent protein label, a component of Ca 2+ indicators, a fluorescent imaging agent, and an anisotropy probe .
Cat. No.: HY-D1422
CAS No.: 1445108-32-6
Synonyms: BDNCa-346
Synonyms: Unoprostone isopropyl ester; UF-021
Target:
Research Areas:
Isopropyl unoprostone (Unoprostone isopropyl ester), an analogue of a prostaglandin metabolite, is a potent large conductance Ca 2+-activated K + (BK) channels activator. Isopropyl unoprostone has antiglaucoma effects, lowering intraocular pressure (IOP) by increasing aqueous humour outflow. Isopropyl unoprostone can improve retinal sensitivity and the protection of central retinal sensitivity .
Synonyms: SSP4
Cat. No.: HY-10167
CAS No.: 148717-54-8
Synonyms: R-568; NPS R-568 free base
Tecalcet (R 568), an orally active calcimimetic compound, allosterically and positively modulates the calcium-sensing receptor (CaSR). Tecalcet (R 568) increases the sensitivity to activation by extracellular Ca 2+ .
Cat. No.: HY-D1424
CAS No.: 123437-32-1
Cat. No.: HY-P5319
Target:
Research Areas:
Cat. No.: HY-176041
CAS No.: 1448792-38-8
Target:
Research Areas:
Troponin modulator 1 (compound 7) modulates the mutant cardiac muscle thin filament function. Troponin modulator 1 enhances Ca 2+ sensitivity by phosphorylation with an EC50 of 67 μM .
Cat. No.: HY-101902
CAS No.: 83104-85-2
Synonyms: Quin-2 acetoxymethyl ester
Cat. No.: HY-DY1095
CAS No.: 121714-22-5
Synonyms: Fluo-3-pentaacetoxymethyl ester (solution)
Solvent and concentration: DMSO: 5 mM
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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
