1 Result for "

Campath-IH

" in MedChemExpress (MCE) Product Catalog:
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1 Results for "Campath-IH" in MCE Product Catalog:

Cat. No.: HY-P9948
CAS No.: 216503-57-0
Synonyms: Campath-IH

Target:  

Apoptosis

Research Areas:  

Cancer

Alemtuzumab (Campath-IH) is a humanized monoclonal antibody against CD52. Alemtuzumab does not cross-react with murine CD52. Alemtuzumab selectively targets the CD52 antigen to induce profound lymphocyte depletion, followed by recovery of T and B cells with regulatory phenotypes. Alemtuzumab is capable of complement-dependent cytotoxicity and antibody-dependent cell-mediated cytotoxicity (ADCC), as well as induction of apoptosis. Alemtuzumab has the potential for B-cell chronic lymphocytic leukaemia research .
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