3 Results for "

Catadegbrutinib

" in MedChemExpress (MCE) Product Catalog:
Products (3)

3 Results for "Catadegbrutinib" in MCE Product Catalog:

Cat. No.: HY-160141
CAS No.: 2736508-60-2
Synonyms: BGB-16673; BTK-IN-29
Target:  

PROTACs Btk NF-κB

Research Areas:  

Inflammation/Immunology Cancer

BGB-16673 (BGB-16673) is an orally active, selective BTK PROTAC degrader (IC50=0.69 nM). BGB-16673 ligates BTK to E3 ubiquitin ligase, causing BTK to undergo polyubiquitination, which is then recognized and degraded by the proteasome, thereby exerting efficient BTK degradation activity. BGB-16673 can be used in the research of B-cell malignancies such as chronic lymphocytic leukemia, small lymphocytic lymphoma, and mantle cell lymphoma .
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Cat. No.: HY-P10326
CAS No.: 1416658-51-9
Target:  

Caspase Apoptosis

Research Areas:  

Cancer

Z-ATAD-FMK is an inhibitor of caspase-12. Z-ATAD-FMK is an inhibitor of caspase-12. Z-ATAD-FMK prevents endoplasmic reticulum stress-mediated apoptosis by inhibiting the activity of caspase-12 and reducing the activity of caspase-9 .
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Cat. No.: HY-175788
Target:  

Btk

Research Areas:  

Cancer

BTK ligand-17 (The Target Protein Ligand Moiety of Catadegbrutinib) is a BTK ligand. BTK can be used as Ligands for Target Protein for PROTAC to develop and design degradative agents for PROTAC BTKs, such as Catadegbrutinib (HY-160141). BTK ligand-17 can also be used in cancer research .
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