Scientific Reviews
Product Guides
Blogs
Topics
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
15 Results for "
Chlorambucil
" in MedChemExpress (MCE) Product Catalog:
Products (15)
15 Results for "Chlorambucil" in MCE Product Catalog:
4
4 Cited Publications
Synonyms: CB-1348; WR-139013
Target:
Research Areas:
Chlorambucil (CB-1348), an orally active antineoplastic agent, is a CNS-penetrant bifunctional alkylating agent belonging to the nitrogen mustard group. Chlorambucil can be used for the research of lymphocytic leukemia, ovarian and breast carcinomas, and Hodgkin’s disease .
2
Category:
Alkaloids Neurological Disease Datura stramonium L. Other Alkaloids Plants Solanaceae Disease Research Fields Endocrinology
Target:
2
2 Cited Publications
Cat. No.: HY-B0459A
CAS No.: 85700-55-6
Synonyms: 6,7-Epoxytropine hydrochloride
Target:
Research Areas:
Scopine hydrochloride is a metabolite of Scopolamine (HY-N0296) and brain-targeting compound. Scopine hydrochloride significantly increases the brain exposure of Chlorambucil (HY-13593) and enhances its anti-glioma activity. Scopine hydrochloride can be used in targeted therapy research for brain gliomas .
Cat. No.: HY-13732
CAS No.: 29069-24-7
Synonyms: Leo 1031; NSC 134087
Target:
Research Areas:
Prednimustine (Leo 1031;NSC 134087) is the ester formed from Prednisolone (HY-17463) and Chlorambucil (HY-13593). Prednimustine can be used for leukemias and lymphomas research .
Cat. No.: HY-178819
Target:
Research Areas:
NM-001 is a theranostic prodrug that targets ανβ3 integrin. NM-001 consists of cRGD and GFLG peptides, a DCM fluorophore and Chlorambucil (HY-13593). NM-001 internalizes into lysosomes of tumor cells via the cRGD peptide, and generates NM-002 (HY-178820) and Chlorambucil through intracellular cleavage at the GFLG peptide by overexpressed Cathepsin B (CTSB). NM-001 exhibits green fluorescence under physiological conditions, and converts to NIR fluorescence by CTSB activation. NM-001 has significant antitumor activity with low toxicity in HeLa cell xenografts mouse models. NM-001 can be used for real-time drug release monitoring research .
Cat. No.: HY-136327
CAS No.: 10477-72-2
Target:
Research Areas:
Phenylacetic acid mustard is the major metabolite of the cancer chemotherapeutic agent Chlorambucil (HY-13593). Chlorambucil is an alkylating agent with antitumor activity .
Cat. No.: HY-19208
CAS No.: 156079-88-8
Target:
Research Areas:
ZD-2767P (Compound 1) is a reversible and competitive inhibitor of IDH1, with its IC50 value being 410 nM .
Research Areas:
Chlorambucil (Standard) is the analytical standard of Chlorambucil. This product is intended for research and analytical applications. Chlorambucil (CB-1348), an orally active antineoplastic agent, is a bifunctional alkylating agent belonging to the nitrogen mustard group. Chlorambucil can be used for the research of lymphocytic leukemia, ovarian and breast carcinomas, and Hodgkin’s disease .
Cat. No.: HY-13593S
CAS No.: 2748247-26-7
Synonyms: CB-1348-d8; WR-139013-d8
Cat. No.: HY-13593S1
CAS No.: 2733532-57-3
Synonyms: CB-1348-d8-1; WR-139013-d8-1
Cat. No.: HY-101999
CAS No.: 141266-44-6
Target:
Research Areas:
EM20-25 is an inhibitor for Bcl-2, which interferes with the interaction between BCL-2 and BAX, activates caspase-9 and thus induces the apoptosis. EM20-25 affects the mitochondrial function, causes the open of permeability transition pore (PTP). EM20-25 enhances the sensitivity of cells to Staurosporine (HY-15141), and enhances the killing effect of BCL-2-expressing leukemia cells to Chlorambucil (HY-13593) and Fludarabine (HY-B0069) .
Cat. No.: HY-123371
CAS No.: 68160-71-4
Ro 07-1902 is a potent antitumor synergist . Ro 07-1902 enhances the antitumor effects of CCNU (HY-13669), Chlorambucil (HY-13593) and Cyclophosphamide (HY-17420). Ro 07-1902 exhibits no single-agent cytotoxicity and does not delay tumor growth. Ro 07-1902 can be used in research related to various cancers .
Synonyms: Bestrabucil; KM2210
Target:
Research Areas:
Atrimustine is a conjugate of chlorambucil and β-estradiol benzoate with the antitumor activity.
Cat. No.: HY-CE01257
Synonyms: Chlorambucil-coenzyme A
Target:
Research Areas:
Chlorambucil-CoA (Chlorambucil-coenzyme A) is a coenzyme A derivative .
Cat. No.: HY-101604R
CAS No.: 75219-46-4
Synonyms: Bestrabucil (Standard); KM2210 (Standard)
Target:
Research Areas:
Atrimustine (Standard) is the analytical standard of Atrimustine. This product is intended for research and analytical applications. Atrimustine is a conjugate of chlorambucil and β-estradiol benzoate with the antitumor activity.
- 1
-
-
Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
