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Cholesterol esters

" in MedChemExpress (MCE) Product Catalog:

39

Inhibitors & Agonists

11

Biochemical Assay Reagents

2

Peptides

8

Natural
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1

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10

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Targets Recommended:
Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-134124
    Glutathione ethyl ester

    		Reactive Oxygen Species (ROS) Metabolic Disease
    Glutathione ethyl ester is a cell-permeable GSH donor and provides an efficient supply of GSH to the oocyte. Glutathione ethyl ester shows positive effect on the in vitro production of embryos by enhancement of the antioxidative defense .
    Glutathione ethyl ester
  • HY-P2879A
    Cholesterol esterase, Porcine pancreas

    		Biochemical Assay Reagents Metabolic Disease
    Cholesterol esterase, Porcine pancreas is an enzyme that hydrolyzes cholesteryl esters into cholesterol and free fatty acids in the intestine. Cholesterol esterase, also known as bile salt-stimulated lipase or carboxyl ester lipase, functions to promote cholesterol absorption .
    Cholesterol esterase, Porcine pancreas
  • HY-W127351
    Cholesterol decanoate

    		Liposome Others
    Cholesterol decanoate is an organic compound belonging to the class of esters. It is formed from the reaction between cholesterol and capric acid. Cholesterol decanoate has several applications in the pharmaceutical industry, particularly as a bioactive compound with potential research potential for improving a range of medical conditions, such as high cholesterol and inflammation-related diseases. Additionally, it has potential applications as a food additive to improve texture and stability.
    Cholesterol decanoate
  • HY-114294A
    DL-3-Hydroxy-3-methylglutaryl coenzyme A disodium hydrate

    HMG-CoA disodium hydrate

    		 Biochemical Assay Reagents Metabolic Disease
    DL-3-Hydroxy-3-methylglutaryl coenzyme A disodium hydrate is a disodium salt compound of HMG-CoA, is a intermediate of terpenes and ketone bodies. DL-3-Hydroxy-3-methylglutaryl coenzyme A disodium also involves in ester metabolism in vivo, as a precursor for cholesterol synthesis, and regulates cholesterol synthesis by coupling LDL receptor .
    DL-3-Hydroxy-3-methylglutaryl coenzyme A disodium hydrate
  • HY-12089
    Torcetrapib

    CP-529414

    		 CETP Endocrinology
    Torcetrapib (CP-529414) is a selective, potent cholesteryl ester transfer protein (CETP) inhibitor. A typical inhibition curve for whole human plasma, having a CETP concentration of 37 nM .
    Torcetrapib
  • HY-N10788
    Pomonic acid

    		Acyltransferase Inflammation/Immunology
    Pomonic acid is an acyl-coenzyme A: cholesterol acyltransferase (ACAT) inhibitor. Pomonic acid reduces the esterification of free cholesterol to cholesteryl esters and the accumulation of intracellular cholesteryl esters. Pomonic acid can be used in the research of atherosclerosis .
    Pomonic acid
  • HY-107396
    YM-750

    		Acyltransferase Cardiovascular Disease
    YM-750 is a potent acyl-CoA:cholesterol acyltransferase (ACAT) inhibitor (IC50=0.18 μM). ACAT catalyzes the formation of cholesteryl esters from cholesterol and long-chain fatty-acyl-coenzyme A .
    YM-750
  • HY-W010695
    Cholesteryl stearate

    		Biochemical Assay Reagents Others
    Cholesteryl stearate is a compound belonging to the class of esters. It is a cholesterol ester commonly found in animal and plant sources. Cholesteryl stearate consists of two naturally occurring substances, cholesteryl alcohol and stearic acid. The combination of the two creates a stable compound that is commonly used in a variety of industrial and biomedical applications. Cholesteryl stearate is commonly used as a lubricant, thickener and emollient in cosmetic formulations such as lotions and creams. It is also used to produce certain types of polymers and plastics.
    Cholesteryl stearate
  • HY-N2339
    Cholesteryl behenate
    1 Publications Verification

    Cholesteryl docosanoate; Cholesterol behenate

    		 Endogenous Metabolite Metabolic Disease
    Cholesteryl behenate is a cholesterol ester associated with the neutral core of low density lipoprotein Receptor-LDL complexes are taken up by lysosomes and hydrolyzed to release cholesterol from the esters.
    Cholesteryl behenate
  • HY-133962
    Cholesteryl erucate

    		Biochemical Assay Reagents Others
    Cholesteryl erucate is a cholesterol ester. It has been used as a standard for the quantification of cholesteryl esters in human meibomian gland secretions.
    Cholesteryl erucate
  • HY-124422
    Pentacosanoic acid

    		Endogenous Metabolite Metabolic Disease
    Pentacosanoic acid is a 25-carbon long-chain saturated fatty acid. Pentacosanoic is a conjugate acid of a pentacosanoate .
    Pentacosanoic acid
  • HY-W414588
    Colestolone

    		HMG-CoA Reductase (HMGCR) CETP Metabolic Disease
    Colestolone is a 15-ketosterol compound and an orally active inhibitor of HMG-CoA reductase. Colestolone can inhibit the activity of cholesteryl ester transfer protein (CETP) in vitro (IC50 = 660 μM). Colestolone is a cholesterol-lowering agent, and can be used in the research of endocrine and metabolic diseases such as hyperlipidemia .
    Colestolone
  • HY-E70599
    Human CES2 Enzyme

    		Carboxylesterase (CES) Metabolic Disease
    Human CES2 Enzyme is a carboxylesterase involved in drug metabolism and lipid homeostasis. Human CES2 Enzyme hydrolyzes triglycerides, cholesteryl esters and retinyl esters to regulate lipid metabolism and energy homeostasis. Human CES2 Enzyme improves glucose tolerance and insulin sensitivity, reduces hepatic lipid accumulation, alleviates white adipose tissue steatitis, decreases plasma cholesterol levels, and reduces body weight and white adipose tissue weight. Human CES2 Enzyme can be used in the research of metabolic syndrome .
    Human CES2 Enzyme
  • HY-P2879B
    Cholesterol esterase, Candida cylindracea

    		Endogenous Metabolite Biochemical Assay Reagents Metabolic Disease
    Cholesterol esterase, Candida cylindracea is an enzyme located in the intestines that hydrolyzes cholesterol esters into cholesterol and free fatty acids. Also known as bile salt-stimulated lipase or carboxylester lipase, this enzyme facilitates cholesterol metabolism and absorption in the body. It can also be used as a biochemical reagent, and is employed in conjunction with cholesterol oxidase (HY-P2848) to measure cholesterol levels .
    Cholesterol esterase, Candida cylindracea
  • HY-120958
    Nisinic acid

    C24:6n-3

    		 Endogenous Metabolite Metabolic Disease
    Nisinic acid (C24:6n-3) is a very long chain polyunsaturated fatty acid (VLCPUFA) that is a component of triglycerides and cholesterol esters in mouse and rat testis .
    Nisinic acid
  • HY-W127331
    Cholesterol hexanoate

    		Liposome Others
    Cholesterol hexanoate is an organic compound belonging to the class of esters. It is formed from the reaction between cholesterol and caproic acid. Cholesterol hexanoate has several applications in the pharmaceutical industry, particularly as a bioactive compound with potential research potential for improving a range of medical conditions, such as high cholesterol and inflammation-related diseases. Additionally, it has potential applications as a food additive to improve texture and stability.
    Cholesterol hexanoate
  • HY-131389
    Cholesteryl heptadecanoate

    		Biochemical Assay Reagents Others
    Cholesteryl heptadecanoate is a cholesteryl ester internal standard that accurately determines the concentration of free cholesterol in cells without hydrolyzing triglycerides. Cholesteryl heptadecanoate can be used for the quantitative determination of cholesteryl esters by GC or LC mass spectrometry .
    Cholesteryl heptadecanoate
  • HY-113086
    CE(16:1(9Z))

    16:1(9Z) CE; 16:1(9Z) Cholesterol ester; Cholesterol Palmitoleate

    		 Endogenous Metabolite Cardiovascular Disease
    CE(16:1(9Z)) (16:1(9Z) CE) is a cholesterol ester. Plasma levels of cholesteryl palmitoleate are increased in ApoE -/- mice exposed to cigarette smoke and in pediatric patients with biliary atresia. Cholesteryl palmitoleate has been used as a standard for the identification of cholesterol esters in human meibomian gland secretions.
    CE(16:1(9Z))
  • HY-W127403
    Cholesteryl elaidate

    Cholesteryl trans-9-octadecenoate

    		 Biochemical Assay Reagents Others
    Cholesteryl elaidate is an organic compound belonging to the class of esters. It is formed from the reaction between cholesterol and elaidic acid, producing a white crystalline solid with a mildly sweet taste. Cholesteryl elaidate has several applications in the pharmaceutical industry, particularly as a bioactive compound with potential research potential for improving a range of medical conditions, such as high cholesterol and inflammation-related diseases. Additionally, it has potential applications as a food additive to improve texture and stability.
    Cholesteryl elaidate
  • HY-P2424
    Cholecystokinin-J

    CCK-J

    		 Calcium Channel Others
    Cholecystokinin-J (CCK-J), a cholecystokinin, stimulates Ca 2+ release .
    Cholecystokinin-J
  • HY-45131
    Cholesterol absorption inhibitor 1

    		Drug Intermediate Metabolic Disease
    Cholesterol absorption inhibitor 1 (compound 21) is a cholesterol absorption inhibitor that reduces liver cholesteryl ester .
    Cholesterol absorption inhibitor 1
  • HY-W127349
    Cholesterol n-Octanoate

    		Liposome Others
    Cholesterol n-Octanoate is an organic compound belonging to the class of esters. It is formed from the reaction between cholesterol and caprylic acid. Cholesterol n-octanoate has various applications in the pharmaceutical industry, notably as a bioactive compound with potential research potential to improve a range of medical conditions, such as high cholesterol and inflammation-related diseases. Additionally, it has potential applications as a food additive to improve texture and stability.
    Cholesterol n-Octanoate
  • HY-124422R
    Pentacosanoic acid (Standard)

    		Reference Standards Endogenous Metabolite Metabolic Disease
    Pentacosanoic acid (Standard) is the analytical standard of Pentacosanoic acid. This product is intended for research and analytical applications. Pentacosanoic acid is a 25-carbon long-chain saturated fatty acid. Pentacosanoic is a conjugate acid of a pentacosanoate[1].
    Pentacosanoic acid (Standard)
  • HY-167025
    Cholesterol laurate

    		Biochemical Assay Reagents Others
    Cholesterol laurate is a cholesterol ester with good biocompatibility, bioavailability and bioactivity. Cholesterol laurate can be used in drug delivery research .
    Cholesterol laurate
  • HY-N15411
    Helminthosporol

    		Acyltransferase Phytohormone Metabolic Disease
    Helminthosporol is a natural plant growth-regulator that can promote the growth of rice and lettuce seedlings. Helminthosporol can also inhibit the activity of acyl-CoA: cholesterol acyltransferase (ACAT) in rat liver microsomes and the synthesis of cholesterol esters in macrophages .
    Helminthosporol
  • HY-N9777
    Procyanidin B-5 3,3'-di-O-gallate

    		Others Metabolic Disease
    Procyanidin B-5 3,3'-di-O-gallate is a potent inhibitor of squalene epoxidase with an IC50 of 0.55 μM. Procyanidin B-5 3,3'-di-O-gallate reduces cholesterol by inhibiting squalene epoxidase activity .
    Procyanidin B-5 3,3'-di-O-gallate
  • HY-N14715
    Gypsetin

    		Acyltransferase Metabolic Disease
    Gypsetin can inhibit acylcoenzyme A, cholesterol acyltransferase (ACAT) activity, inhibit rat liver microbody ACAT with an IC50 of 18 μM, and its action is competitive with oleoyl-COA substrate, Ki value is 5.5 μM. Gypsetin also inhibits Oleic acid from forming cholesterol esters with an IC50 of 0.65 μM .
    Gypsetin
  • HY-W127349R
    Cholesterol n-Octanoate (Standard)

    		Liposome Reference Standards Others
    Cholesterol n-Octanoate (Standard) is the analytical standard of Cholesterol n-Octanoate. This product is intended for research and analytical applications. Cholesterol n-Octanoate is an organic compound belonging to the class of esters. It is formed from the reaction between cholesterol and caprylic acid. Cholesterol n-octanoate has various applications in the pharmaceutical industry, notably as a bioactive compound with potential research potential to improve a range of medical conditions, such as high cholesterol and inflammation-related diseases. Additionally, it has potential applications as a food additive to improve texture and stability.
    Cholesterol n-Octanoate (Standard)
  • HY-129340
    AS-183

    		Acyltransferase Cardiovascular Disease
    AS-183 is an inhibitor of cholesterol acyltransferase (ACAT) (IC50=0.94 µM). AS-183 also inhibits the formation of cholesterol esters in HepG2, CaCo2 and THP-1 cells with IC50 values ​​of 18.1, 25.5 and 34.5 µM, respectively. AS-183 can be used in the study of atherosclerosis and hypercholesterolemia .
    AS-183
  • HY-169321
    20:2 (11,14) Cholesterol ester

    		Biochemical Assay Reagents Metabolic Disease
    20:2 (11,14) Cholesterol ester is a cholesterol ester that can be used as a synthetic intermediate in the synthesis of cholesterol methyl esters.
    20:2 (11,14) Cholesterol ester
  • HY-P2879H
    Cholesterol Esterase, PEG Modified

    		Biochemical Assay Reagents Others
    Cholesterol esterase, PEG Modified, is a polyethylene glycol (PEG) modified cholesterol esterase. Cholesterol esterase is an enzyme that catalyzes the hydrolysis of cholesterol esters into sterols and fatty acids.
    Cholesterol Esterase, PEG Modified
  • HY-P2879C
    Cholesterol esterase, schizophyllum commune

    		Endogenous Metabolite Metabolic Disease
    Cholesterol esterase, Schizophyllum commune is an enzyme that catalyzes the hydrolysis of cholesterol esters into free cholesterol and fatty acids, facilitating the absorption of cholesterol in the intestine. Cholesterol esterase, Schizophyllum commune can be used in combination with cholesterol oxidase to measure cholesterol content .
    Cholesterol esterase, schizophyllum commune
  • HY-167024
    Cholesterol valerate

    		Biochemical Assay Reagents Others
    Cholesterol valerate is a cholesterol ester with good biocompatibility, bioavailability and bioactivity. Cholesterol valerate can be used in drug delivery research .
    Cholesterol valerate
  • HY-P2879D
    Cholesterol esterase, Candida Rugosa

    		Biochemical Assay Reagents Metabolic Disease
    Cholesterol esterase, Candida Rugosa (EC 3.1.1.13), catalyzes the synthesis of sterols and fatty acids from sterol esters. In the presence of bile acids, it aggregates to form a hexamer, which may be the active form of this enzyme.
    Cholesterol esterase, Candida Rugosa
  • HY-181462
    Desmosteryl linoleate

    		Drug Derivative Others
    Desmosteryl linoleate is an ester formed by Desmosterol (HY-113224) and Linoleic acid (HY-N0729) .
    Desmosteryl linoleate
  • HY-107396R
    YM-750 (Standard)

    		Reference Standards Acyltransferase Cardiovascular Disease
    YM-750 (Standard) is the analytical standard of YM-750 (HY-107396). This product is intended for research and analytical applications. YM-750 is a potent acyl-CoA:cholesterol acyltransferase (ACAT) inhibitor (IC50=0.18 μM). ACAT catalyzes the formation of cholesteryl esters from cholesterol and long-chain fatty-acyl-coenzyme A .
    YM-750 (Standard)
  • HY-18778B
    Obicetrapib potassium

    TA-8995 potassium; DEZ-001 potassium; AMG-899 potassium

    		 Apolipoprotein CETP LPL Receptor LDLR Metabolic Disease
    Obicetrapib (TA-8995; DEZ-001) potassium is an orally active cholesteryl ester transfer protein (CETP) inhibitor. Obicetrapib potassium potently reduces atherogenic lipoproteins (such as LDL-C, ApoB, Lp (a)) and increases HDL-C. Obicetrapib potassium can be used for the research of dyslipidemia and atherosclerotic cardiovascular disease (ASCVD) .
    Obicetrapib potassium
  • HY-W010695R
    Cholesteryl stearate (Standard)

    		Biochemical Assay Reagents Reference Standards Others
    Cholesteryl stearate (Standard) is the analytical standard of Cholesteryl stearate (HY-W010695). This product is intended for research and analytical applications. Cholesteryl stearate is a compound belonging to the class of esters. It is a cholesterol ester commonly found in animal and plant sources. Cholesteryl stearate consists of two naturally occurring substances, cholesteryl alcohol and stearic acid. The combination of the two creates a stable compound that is commonly used in a variety of industrial and biomedical applications. Cholesteryl stearate is commonly used as a lubricant, thickener and emollient in cosmetic formulations such as lotions and creams. It is also used to produce certain types of polymers and plastics.
    Cholesteryl stearate (Standard)
  • HY-W010695S1
    Cholesteryl octadecanoate-d35

    		Isotope-Labeled Compounds Biochemical Assay Reagents Others
    Cholesteryl octadecanoate-d35 is the deuterium labeled Cholesteryl stearate (HY-W010695). Cholesteryl stearate is a compound belonging to the class of esters. It is a cholesterol ester commonly found in animal and plant sources. Cholesteryl stearate consists of two naturally occurring substances, cholesteryl alcohol and stearic acid. The combination of the two creates a stable compound that is commonly used in a variety of industrial and biomedical applications. Cholesteryl stearate is commonly used as a lubricant, thickener and emollient in cosmetic formulations such as lotions and creams. It is also used to produce certain types of polymers and plastics.
    Cholesteryl octadecanoate-d35

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