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Cat. No.: HY-114294A

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DL-3-Hydroxy-3-methylglutaryl coenzyme A disodium hydrate

Name: DL-3-Hydroxy-3-methylglutaryl coenzyme A disodium hydrate
Brand: MedChemExpress
SKU: HY-114294A
Price: 300.00 USD
Availability: InStock
Rating: 5 (1 reviews)

(Synonyms: HMG-CoA disodium hydrate)

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DL-3-Hydroxy-3-methylglutaryl coenzyme A disodium hydrate is a disodium salt compound of HMG-CoA, is a intermediate of terpenes and ketone bodies. DL-3-Hydroxy-3-methylglutaryl coenzyme A disodium also involves in ester metabolism in vivo, as a precursor for cholesterol synthesis, and regulates cholesterol synthesis by coupling LDL receptor.

For research use only. We do not sell to patients.

Purity : 99.0%
CAS No.: 103476-21-7
Formula: C₂₇H₄₄N₇Na₂O₂₁P₃S.xH₂O

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

DL-3-Hydroxy-3-methylglutaryl coenzyme A disodium hydrate Chemical Structure

CAS No.: 103476-21-7

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Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- In Vitro
Chemical Information
Solvent & Solubility
- In Vitro
Purity & Documentation
References
Calculators
Help & FAQs
Classifications
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Biological Activity

Description

In Vitro

DL-3-Hydroxy-3-methylglutaryl coenzyme A disodium hydrate comes from acetyl-coa and acetyl-CoA converted from HMG-CoA synthetase, mainly dependents on oxidative reactions in mitochondria^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 103476-21-7
Appearance Solid
Formula C₂₇H₄₄N₇Na₂O₂₁P₃S.xH₂O
Color White to off-white
SMILES

O[C@@H]1[C@H](OP(O)(O)=O)[C@H](O[C@H]1N2C(N=CN=C3N)=C3N=C2)COP(OP(OCC(C)(C)[C@@H](O)C(NCCC(NCCSC(CC(C)(O)CC(O)=O)=O)=O)=O)(O[Na])=O)(O[Na])=O.[x].O
Synonyms

HMG-CoA disodium hydrate
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Solvent & Solubility

In Vitro:

H2O : 50 mg/mL (Need ultrasonic and warming)

View the Complete Stock Solution Preparation Table

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (268 KB)
SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Millán Núñez-Cortés J, et al. Fármacos hipolipemiantes y PCSK9 [Lipid-lowering drugs and PCSK9]. Clin Investig Arterioscler. 2016 May;28 Suppl 2:9-13. Spanish. [Content Brief]

[2]. Wang Wei, er al. The Key Enzyme of Cholesterol Synthesis Pathway:HMG CoA Reductase and Disease. PROGRESS IN PHYSIOLOGICAL SCIENCES. 1999. (01):7-11.

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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DL-3-Hydroxy-3-methylglutaryl coenzyme A disodium hydrate

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DL-3-Hydroxy-3-methylglutaryl coenzyme A disodium hydrate

Biological Activity

Description

In Vitro

Chemical Information

Solvent & Solubility

In Vitro:

Purity & Documentation

References

Calculators

Help & FAQs

DL-3-Hydroxy-3-methylglutaryl coenzyme A disodium hydrate Related Classifications

HY-114294A Related Classifications

Bioz

Keywords

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