1 Result for "

DC-Y13-27

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "DC-Y13-27" in MCE Product Catalog:

6
6 Cited Publications
Cat. No.: HY-154919
Purity:  99.52%
Research Areas:  

Endocrinology Cancer

DC-Y13-27 is a DC-Y13 derivative and YTHDF2 inhibitor (KD: 37.9 μM). DC-Y13-27 inhibits YTHDF2, restores FOXO3 and TIMP1 protein levels, and reduces MMP1/3/7/9 expression. DC-Y13-27 induces Pyroptosis and increases IL-1β secretion. DC-Y13-27 reduces intervertebral disc degeneration and enhances the response to radiotherapy in colon cancer and melanoma. DC-Y13-27 has antitumor activity against breast cancer .
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