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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
19 Results for "
DCK
" in MedChemExpress (MCE) Product Catalog:
Products (19)
19 Results for "DCK" in MCE Product Catalog:
Cat. No.: HY-164840A
Target:
Research Areas:
Clofarabine-5'-triphosphate trisodium is the trisodium salt form of Clofarabine-5'-triphosphate (HY-164840). Clofarabine-5'-triphosphate trisodium is the metabolite of Clofarabine (HY-A0005) by deoxycytidine kinase (dCK) phosphorylation. Clofarabine-5'-triphosphate trisodium exhibits cytotoxicity in cancer cells through inhibition of DNA synthesis and DNA repair .
Cat. No.: HY-169347
CAS No.: 3085297-83-9
Synonyms: LC-05-004
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Research Areas:
dCK1α-2 is an orally active CK1α molecular glue degrader that targets p53 pathway-related targets. dCK1α-2 exhibits anti-tumor efficacy in mouse models and can increase the expression of p53-related genes. .
Cat. No.: HY-14509
CAS No.: 1034174-88-3
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LP-661438 (Compound 10) is an orally active DCK inhibitor (IC50 = 1.7 nM). LP-661438 inhibits deoxycytidine kinase in T cells and in vivo .
Cat. No.: HY-RS03577
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DCK Human Pre-designed siRNA Set A contains three designed siRNAs for DCK gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS24804
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Research Areas:
Dck Rat Pre-designed siRNA Set A contains three designed siRNAs for Dck gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-164840
CAS No.: 134646-41-6
Synonyms: Clofarabine-TP
Target:
Research Areas:
Clofarabine-5'-triphosphate is the metabolite of Clofarabine (HY-A0005) by deoxycytidine kinase (dCK) phosphorylation. Clofarabine-5'-triphosphate exhibits cytotoxicity in cancer cells through inhibition of DNA synthesis and DNA repair .
Cat. No.: HY-W194107
CAS No.: 1209784-87-1
Target:
Research Areas:
Antitumor agent-152 (Compound 5) is a specific substrate and inhibitor of deoxycytidine kinase (dCK) with anticancer activity. Antitumor agent-152 can inhibit the uptake of 3H-dC in L1210 leukemia cells with an IC50 value of 1.12 μM .
Cat. No.: HY-164839
CAS No.: 167620-89-5
Synonyms: Clofarabine-DP
Target:
Research Areas:
Clofarabine-5'-diphosphate (Clofarabine-DP) is the metabolite of Clofarabine (HY-A0005) by deoxycytidine kinase (dCK) phosphorylation. Clofarabine-5'-diphosphate can be further phorphorylated into Clofarabine-5'-triphosphate, and exhibits cytotoxicity in cancer cells through inhibition of DNA synthesis and DNA repair .
Cat. No.: HY-P700584
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: rHuDeoxycytidine kinase/DCK, His-T7; Deoxycytidine Kinase; DCK; DCK
Species:
Source:
Cat. No.: HY-164839A
Synonyms: Clofarabine-DP trisodium
Target:
Research Areas:
Clofarabine-5'-diphosphate trisodium (Clofarabine-DP trisodium) is the trisodium salt form of Clofarabine-5'-diphosphate (HY-164839). Clofarabine-5'-diphosphate trisodium is the metabolite of Clofarabine (HY-A0005) by deoxycytidine kinase (dCK) phosphorylation. Clofarabine-5'-diphosphate trisodium can be further phorphorylated into Clofarabine-5'-triphosphate, and exhibits cytotoxicity in cancer cells through inhibition of DNA synthesis and DNA repair .
Cat. No.: HY-RS18325
Target:
Research Areas:
Dck Mouse Pre-designed siRNA Set A contains three designed siRNAs for Dck gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-P702661
Purity: ≥ 80%, as determined by reducing SDS-PAGE.
Synonyms: DCLK2; doublecortin like kinase 2; CL2; DCK2; CLIK2; DCDC3; CLICK2; DCDC3B; DCAMKL2; CLICK-II
Species:
Source:
Cat. No.: HY-P705803
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: DCLK2; doublecortin like kinase 2; CL2; DCK2; CLIK2; DCDC3; CLICK2; DCDC3B; DCAMKL2; CLICK-II
Species:
Source:
Cat. No.: HY-P706031
Purity: ≥ 85%, as determined by reducing SDS-PAGE.
Synonyms: Serine/threonine-protein kinase DCLK2; CaMK-like CREB regulatory kinase 2; CL2; CLICK-II; CLICK2; Doublecortin domain-containing protein 3B; Doublecortin-like and CAM kinase-like 2; Doublecortin-like kinase 2; DCAMKL2; DCDC3B; DCK2
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
