DCLK2 Antibody (YA4370)
(Synonyms: CL2; DCK2; CLIK2; DCDC3; CLICK2; DCDC3B; DCAMKL2; CLICK-II)DCLK2 Antibody (YA4370) is a Mouse-derived and non-conjugated IgG2a monoclonal antibody, targeting to DCLK2.
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Host:
Mouse
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Isotype:
IgG2a
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Application:
IHC-P, FC, ELISA
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Reactivity :
Human
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Formulation:
Supplied in PBS with 0.05% sodium azide
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Conjugation:
Non-conjugated
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
Applications
| Application |
IHC-P
IHC-P: Immunohistochemistry-Paraffin
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FC
FC: Flow Cytometry
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ELISA
ELISA: Enzyme Linked Immunosorbent Assay
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|---|---|---|---|
| Dilution Ratio | 1:200-1:1000 | 1:200-1:400 | 1:10000 |
Product Details
DCLK2 Antibody (YA4370) is a Mouse-derived and non-conjugated IgG2a monoclonal antibody, targeting to DCLK2.
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Host Mouse
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Clonality Monoclonal
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Species ReactivityHuman
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Observed Molecular WeightObserved band size: 84 kDa
Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.
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Calculated Molecular Weight Predicted band size: 83.6 kDa
Purified recombinant fragment of human DCLK2 (AA: 652-766) expressed in mammalian.
affinity purified.
Non-conjugated
Unmodified
IgG2a
Product Properties
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Appearance
Liquid
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Formulation
Supplied in PBS with 0.05% sodium azide
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Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
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Shipping
Shipping with blue ice.
Background
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Function
DCLK2 is a Protein kinase with a significantly reduced C(a2+)/CAM affinity and dependence compared to other members of the CaMK family. May play a role in the down-regulation of CRE-dependent gene activation probably by phosphorylation of the CREB coactivator CRTC2/TORC2 and the resulting retention of TORC2 in the cytoplasm
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Subcellular Localization
Cytoplasm, cytoskeleton
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Expression
Tissue_specificity:Expressed in the brain, heart and eyes -
Isoforms & Post-Translational Modification
Q8N568 has 3 isomers: Q8N568-1: 83606 Da (predicted); Q8N568-2: 83478 Da (predicted); Q8N568-3: 85384 Da (predicted).
Autophosphorylated -
Subunit
Binds to and stabilizes microtubules. Interacts with MAPK8IP1/JIP-1, MAPK8IP2/JIP-2, MAPK9/JNK2, PPP1R9B/NEURABIN-2 and actin
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SwissProt ID
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Synonyms
CL2; DCK2; CLIK2; DCDC3; CLICK2; DCDC3B; DCAMKL2; CLICK-II
Documentation
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