DCLK2 Antibody (YA4370)(PBS only)

Cat. No.: HY-P84673A: Data Sheet User Guide for Antibodies
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DCLK2 Antibody (YA4370) is a Mouse-derived and non-conjugated IgG2a monoclonal antibody, targeting to DCLK2.

For research use only. We do not sell to patients.

Size		Stock
50 μL		Get quote
100 μL		Get quote

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WB: Western Blot;
IHC-P: Immunohistochemistry-Paraffin;
IHC-F: Immunohistochemistry-Frozen;
ICC/IF: Immunocytochemistry/Immunofluorescence;
IF-Tissue: Immunofluorescence-Tissue;
mIHC: Multiplex Immunohistochemical;
IP: Immunoprecipitation;
ChIP: Chromatin Immunoprecipitation;
FC: Flow Cytometry;
ELISA: Enzyme Linked Immunosorbent Assay

Product Detail
Background
Documentation

Description

DCLK2 Antibody (YA4370) is a Mouse-derived and non-conjugated IgG2a monoclonal antibody, targeting to DCLK2.

Host

Mouse

Molecular Weight

Predicted band size: 83.6 kDa;

Observed band size: 84 kDa

Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.

Species Reactivity

Human

SwissProt ID

Q8N568

Gene ID

166614 [NCBI]

Immunogen

Purified recombinant fragment of human DCLK2 (AA: 652-766) expressed in mammalian.

Application &
Dilution Ratio

Application	Dilution Ratio
IHC-P IHC-P: Immunohistochemistry-Paraffin	1:200-1:1000
FC FC: Flow Cytometry	1:200-1:400
ELISA ELISA: Enzyme Linked Immunosorbent Assay	1:10000

Purity	affinity purified.	Conjugation	Non-conjugated
Isotype	IgG2a

Appearance

Liquid

Formulation

Supplied in PBS, pH 7.4.

Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

Shipping

Shipping with blue ice.

Background

Function：Protein kinase with a significantly reduced C(a2+)/CAM affinity and dependence compared to other members of the CaMK family. May play a role in the down-regulation of CRE-dependent gene activation probably by phosphorylation of the CREB coactivator CRTC2/TORC2 and the resulting retention of TORC2 in the cytoplasm (By similarity)

Subcellular Localization：Cytoplasm, cytoskeleton

Expression：
Tissue_specificity:Expressed in the brain, heart and eyes

Isoforms & Post-Translational Modification：Q8N568 has 3 isomers: Q8N568-1: 83606 Da (predicted); Q8N568-2: 83478 Da (predicted); Q8N568-3: 85384 Da (predicted).
Autophosphorylated

Subunit：Binds to and stabilizes microtubules. Interacts with MAPK8IP1/JIP-1, MAPK8IP2/JIP-2, MAPK9/JNK2, PPP1R9B/NEURABIN-2 and actin

Synonyms

CL2; DCK2; CLIK2; DCDC3; CLICK2; DCDC3B; DCAMKL2; CLICK-II

Documentation

User Guide for Antibodies (1077 KB)