1034174-88-3
1034174-88-3
Chemical Structure
LP-661438
- No. CAS: 1034174-88-3
- Formula:C23H20FN5O2S
- Molecular Weight:449.50
IUPAC Name: N-((1S,3S)-3-(4-amino-5-fluoro-2-oxopyrimidin-1(2H)-yl)cyclopentyl)-4-(benzo[b]thiophen-2-yl)picolinamide
InChIKey: YBTIDKMFVSZULE-HOTGVXAUSA-N
SMILES: O=C(N[C@H]1CC[C@H](N2C(N=C(N)C(F)=C2)=O)C1)C3=NC=CC(C4=CC5=CC=CC=C5S4)=C3
Biological Activity: LP-661438 (Compound 10) is an orally active DCK inhibitor (IC50 = 1.7 nM). LP-661438 inhibits deoxycytidine kinase in T cells and in vivo[1].
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LP-661438 | LP-661438 (Compound 10) is an orally active DCK inhibitor (IC50 = 1.7 nM). LP-661438 inhibits deoxycytidine kinase in T cells and in vivo. | |||||||||||||||||||||
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References
Keywords
