2 Results for "

DHPG (Standard)

" in MedChemExpress (MCE) Product Catalog:
Products (2)

2 Results for "DHPG (Standard)" in MCE Product Catalog:

Cat. No.: HY-12598AR
CAS No.: 146255-66-5
Synonyms: (RS)-3,5-DHPG (Standard)
Research Areas:  

Neurological Disease

DHPG (Standard) is the analytical standard of DHPG. This product is intended for research and analytical applications. DHPG is the agonist for mGluR 1/5 (EC50 for mGluR 1 is 60 nM) that activates the phospholipase C (PLC) pathway, and leads ultimately to the activation of protein kinase C (PKC) .
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Cat. No.: HY-103566R
CAS No.: 338736-46-2
LY456236 (Standard) is the analytical standard of LY456236 (HY-103566). This product is intended for research and analytical applications. LY456236 is a selective, non-competitive and orally active antagonist of glutamate receptor 1 (mGlu1), which can inhibit phosphatidylinositol hydrolysis with an IC50 of 0.145 μM. LY456236 can also inhibit EGFR, with an IC50 of 0.918 μM. LY456236 has anticonvulsant effects and blocks cell proliferation by inhibiting the MAPK pathway, reversing the anti-apoptotic effect of DHPG (HY-12598A). LY456236 can be used in epilepsy research .
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