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Results for "

DVL2

" in MedChemExpress (MCE) Product Catalog:

5

Inhibitors & Agonists

1

Fluorescent Dyes

1

Biochemical Assay Reagents

1

Antibodies

1

Oligonucleotides

1

GMP Molecules

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-15825
    IWP L6
    4 Publications Verification

    Porcn Inhibitor III

    		 Porcupine Cancer
    IWP L6 (Porcn Inhibitor III) is a Porcupine (Porcn) inhibitor with an EC50 of 0.5 nM. IWP L6 disrupts well-established Wnt-dependent developmental processes of embryonic and juvenile zebrafish .
    IWP L6
  • HY-100853
    IWP-O1

    		Porcupine Wnt Cancer
    IWP-O1 is a highly potent Porcupine (Porcn) inhibitor, with an EC50 of 80 pM in L-Wnt-STF cells. IWP-O1 prevents the secretion of Wnt proteins. IWP-O1 suppresses the phosphorylation of Dvl2/3 and LRP6 in HeLa cells .
    IWP-O1
  • HY-RS04077
    DVL2 Human Pre-designed siRNA Set A

    		Small Interfering RNA (siRNA) Others

    DVL2 Human Pre-designed siRNA Set A contains three designed siRNAs for DVL2 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

    DVL2 Human Pre-designed siRNA Set A
    DVL2 Human Pre-designed siRNA Set A
  • HY-15825G
    IWP L6

    Porcn Inhibitor III

    		 Porcupine Cancer
    IWP L6 (GMP) (Porcn Inhibitor III (GMP)) is IWP L6 (HY-15825) produced by using GMP guidelines. GMP small molecules works appropriately as an auxiliary reagent for cell therapy manufacture. IWP L6 (Porcn Inhibitor III) is a Porcupine (Porcn) inhibitor with an EC50 of 0.5 nM. IWP L6 disrupts well-established Wnt-dependent developmental processes of embryonic and juvenile zebrafish .
    IWP L6
  • HY-N0836A
    Jervine hydriodide

    11-Ketocyclopamine hydriodide

    		 Hedgehog Wnt Akt mTOR AMPK DNA/RNA Synthesis Apoptosis Autophagy Reactive Oxygen Species (ROS) Mitochondrial Metabolism Inflammation/Immunology Cancer
    Jervine hydriodide is an orally active steroidal alkaloid and Hedgehog signaling pathway inhibitor. Jervine hydriodide can be isolated from Veratrum californicum. Jervine hydriodide regulates Wnt, inhibits the AKT/mTOR signaling pathway, and activates the AMPK signaling pathway. Jervine hydriodide induces DNA damage, Apoptosis, Autophagy, ROS production and Mitochondrial damage. Jervine hydriodide exhibits anti-cancer and anti-inflammatory activities. Jervine hydriodide reduces tumor growth rate and weight in xenograft models. Jervine hydriodide can be used in studies related to triple-negative breast cancer, nasopharyngeal carcinoma and non-small cell lung cancer [2] .
    Jervine hydriodide

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