2074607-48-8
2074607-48-8
Chemical Structure
IWP-O1
- CAS No.: 2074607-48-8
- Formula:C26H20N6O
- Molecular Weight:432.48
IUPAC Name: 2-(5-phenyl-4-(pyridin-4-yl)-1H-1,2,3-triazol-1-yl)-N-(5-phenylpyridin-2-yl)acetamide
InChIKey: GYYDQHBKIHQHEB-UHFFFAOYSA-N
SMILES: O=C(CN1N=NC(C2=CC=NC=C2)=C1C3=CC=CC=C3)NC4=NC=C(C5=CC=CC=C5)C=C4
Biological Activity: IWP-O1 is a highly potent Porcupine (Porcn) inhibitor, with an EC50 of 80 pM in L-Wnt-STF cells. IWP-O1 prevents the secretion of Wnt proteins. IWP-O1 suppresses the phosphorylation of Dvl2/3 and LRP6 in HeLa cells[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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IWP-O1 | 99.81% | IWP-O1 is a highly potent Porcupine (Porcn) inhibitor, with an EC50 of 80 pM in L-Wnt-STF cells. IWP-O1 prevents the secretion of Wnt proteins. IWP-O1 suppresses the phosphorylation of Dvl2/3 and LRP6 in HeLa cells. | ||||||||||||||||||||
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References
Keywords
