2 Results for "

EGFR-IN-151

" in MedChemExpress (MCE) Product Catalog:
Products (2)

2 Results for "EGFR-IN-151" in MCE Product Catalog:

Cat. No.: HY-173038
Target:  

EGFR ERK STAT Apoptosis

Research Areas:  

Cancer

EGFR-IN-151 (Compound 10) inhibits EGFR and its downstream signaling pathways ERK/STAT3. EGFR-IN-151 inhibits the proliferation of a variety lung cancer cells (IC50s for NCI-H1781, HCC827, NCI-H3255 and NCI-H1975 is 11.7, 5.19, 7.32 and 1.53 μM, respectively), inhibits the colony formation and migration of H1975, arrests the cell cycle at G1 phase, and induces apoptosis in H1975 .
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Cat. No.: HY-P991572
CAS No.: 1399724-72-1

Target:  

EGFR

Research Areas:  

Cancer

MM-151 is a humanized IgG1 monoclonal antibody targeting EGFR. MM-151 binds multiple regions of the EGFR extracellular domain (ECD) and reduces its mutations in circulating cell-free tumor DNA with EGFR resistance. MM-151 significantly inhibits EGFR signaling and cell growth. MM-151 can be used for drug-resistant cancers research, such as colorectal, non-small cell lung and triple negative breast cancer .
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