EGFR-IN-151
EGFR-IN-151 (Compound 10) inhibits EGFR and its downstream signaling pathways ERK/STAT3. EGFR-IN-151 inhibits the proliferation of a variety lung cancer cells (IC50s for NCI-H1781, HCC827, NCI-H3255 and NCI-H1975 is 11.7, 5.19, 7.32 and 1.53 μM, respectively), inhibits the colony formation and migration of H1975, arrests the cell cycle at G1 phase, and induces apoptosis in H1975.
For research use only. We do not sell to patients.
- Formula: C55H59N9O18
- Molecular Weight:1134.11
-
Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
Biological Activity
-
Chemical Information
- Purity & Documentation
- References
-
Help & FAQs
All EGFR Isoforms
More
Biological Activity
Chemical Information
-
Molecular Weight 1134.11
-
Formula C55H59N9O18
-
SMILES
O=C(O[C@H]1[C@@H](C2=CC(O)=C(O)C(O)=C2)OC3=C(C(OCC4=CN(CCOCCOCCOCCN5N=NC(C6=CC=CC(NC7=C8C=C(OCCOC)C(OCCOC)=CC8=NC=N7)=C6)=C5)N=N4)=CC(O)=C3)C1)C9=CC(O)=C(O)C(O)=C9
-
Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
EGFR-IN-151 Related Classifications
HY-173038 Related Classifications
Powered by Bioz