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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
84 Results for "
ERBB1
" in MedChemExpress (MCE) Product Catalog:
Products (84)
84 Results for "ERBB1" in MCE Product Catalog:
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2
2 Cited Publications
Cat. No.: HY-P72987
Purity: ≥ 75%, as determined by reducing SDS-PAGE.
Synonyms: Epidermal growth factor receptor; EGFR; ERBB; ERBB1; HER1
Species:
Source:
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1 Cited Publications
Cat. No.: HY-168438
CAS No.: 930856-19-2
Research Areas:
ERBB agonist-1 is a ERBB4 agonist with an EC50 of 10.5 μM. ERBB agonist-1 enhances NRG1-induced ERBB4 homodimerization and activates the PI3K/Akt and MAPK/ERK signaling pathways. ERBB agonist-1 acts as a cell survival promoter, anti-hypertrophic agent, anti-fibrotic agent, and cardioprotective agent. ERBB agonist-1 is applicable to the research of heart failure [1].
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1 Cited Publications
Cat. No.: HY-P80116
Synonyms: Avian erythroblastic leukemia viral (v erb b) oncogene homolog antibody;
Cell growth inhibiting protein 40 antibody;
Cell proliferation inducing protein 61 antibody;
EGF R antibody;
EGFR antibody;
EGFR_HUMAN antibody;
Epidermal growth factor receptor (avian erythroblastic leukemia viral (v erb b) oncogene homolog) antibody;
Epidermal growth factor receptor antibody;
erb-b2 receptor tyrosine kinase 1 antibody;
ERBB antibody;
ERBB1 antibody;
Errp antibody;
HER1 antibody;
mENA antibody;
NISBD2 antibody;
Oncogen ERBB antibody;
PIG61 antibody;
Proto-oncogene c-ERBB-1 antibody;
Receptor tyrosine protein kinase ERBB 1 antibody;
Receptor tyrosine-protein kinase ERBB-1 antibody;
SA7 antibody;
Species antigen 7 antibody;
Urogastrone antibody;
v-erb-b Avian erythroblastic leukemia viral oncogen homolog antibody;
wa2 antibody;
Wa5 antibody
EGFR/ErbB-2/ErbB-4 inhibitor-3 (compound 29) is a potent tyrosine kinase inhibitor with IC50s of 0.3, 1.1, 0.5, 2.5, 24 nM for erbB1, erbB2, erbB4, EGF, HER, respectively [1]. EGFR/ErbB-2/ErbB-4 inhibitor-3 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
Cat. No.: HY-E70715
The erbB family comprises 4 structurally related receptors: ErbB1 (EGFR), ErbB2 (HER2-neu), ErbB3 and ErbB4. On ligand stimulation, the receptor forms either homodimers or heterodimers, which activate their cytoplasmic domain. ERBB2 775YVMA776 Recombinant Human Active Protein Kinase is a recombinant ERBB2 775YVMA776 protein that can be used to study ERBB2 775YVMA776-related functions [1].
JNJ28871063 hydrochloride is an orally active, highly selective and ATP competitive pan-ErbB kinase inhibitor with IC50 values of 22 nM, 38 nM, and 21 nM for ErbB1, ErbB2, and ErbB4, respectively. JNJ28871063 hydrochloride inhibits phosphorylation of functionally important tyrosine residues in both EGFR and ErbB2. JNJ28871063 hydrochloride crosses the blood-brain barrier and has antitumor activity in human tumor xenograft models that overexpress EGFR and ErbB2 [1].
Cat. No.: HY-RS04209
Target:
Research Areas:
EGFR Human Pre-designed siRNA Set A contains three designed siRNAs for EGFR gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-P990408
Target:
Research Areas:
Cat. No.: HY-P990409
Target:
Research Areas:
Cat. No.: HY-137028
CAS No.: 136904-69-3
Synonyms: PD157432
2'-Thioadenosine (PD157432) is a selective and irreversible inhibitor of ErbB-1 and ErbB-2, with an IC50 of 45 µM for ErbB-2. 2'-Thioadenosine covalently inactivates ErbB-1 via modification of a cysteine residue at the active site [1].
Cat. No.: HY-123726
CAS No.: 231277-83-1
ErbB-1/ErbB-2 tyrosine kinase-IN-1 is a dual ErbB-1/ErbB-2 tyrosine kinase inhibitor with IC50 values of 0.027 μM and 0.026 μM. ErbB-1/ErbB-2 tyrosine kinase-IN-1 targets the ATP binding region of ErbB-1 and ErbB-2 tyrosine kinases. ErbB-1/ErbB-2 tyrosine kinase-IN-1 inhibits cancer cells proliferation [1].
Cat. No.: HY-P992138
CAS No.: 3030203-93-8
Research Areas:
Cat. No.: HY-P706036
Purity: ≥ 85%, as determined by reducing SDS-PAGE.
Synonyms: Epidermal growth factor receptor; Proto-oncogene c-ERBB-1; Receptor tyrosine-protein kinase ERBB-1; ERBB; ERBB1; HER1
Species:
Source:
Cat. No.: HY-P706038
Purity: ≥ 85%, as determined by reducing SDS-PAGE.
Synonyms: Epidermal growth factor receptor; Proto-oncogene c-ERBB-1; Receptor tyrosine-protein kinase ERBB-1; ERBB; ERBB1; HER1
Species:
Source:
Cat. No.: HY-P706040
Purity: ≥ 85%, as determined by reducing SDS-PAGE.
Synonyms: Epidermal growth factor receptor; Proto-oncogene c-ERBB-1; Receptor tyrosine-protein kinase ERBB-1; ERBB; ERBB1; HER1
Species:
Source:
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
