930856-19-2
930856-19-2
Chemical Structure
ERBB agonist-1
- CAS No.: 930856-19-2
- Formula:C24H25N3O2S
- Molecular Weight:419.54
InChIKey: HPAVQFJCKMYFSE-UHFFFAOYSA-N
SMILES: O=C(NC1CC1)C(SC(N2C3CCCC3)=NC4=CC=CC=C4C2=O)C5=CC=CC=C5
Biological Activity: ERBB agonist-1 is a ERBB4 agonist with an EC50 of 10.5 μM. ERBB agonist-1 enhances NRG1-induced ERBB4 homodimerization. ERBB agonist-1 acts as a cell survival promoter, anti-hypertrophic agent, anti-fibrotic agent, and cardioprotective agent. ERBB agonist-1 is applicable to the research of heart failure[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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ERBB agonist-1 | 99.16% | ERBB agonist-1 is a ERBB4 agonist with an EC50 of 10.5 μM. ERBB agonist-1 enhances NRG1-induced ERBB4 homodimerization. ERBB agonist-1 acts as a cell survival promoter, anti-hypertrophic agent, anti-fibrotic agent, and cardioprotective agent. ERBB agonist-1 is applicable to the research of heart failure. | ||||||||||||||||||||
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Structural Analogs
-
Similarity Score 0.53
HY-1175731Z105 -
Similarity Score 0.52
HY-150089SRI-37240 -
Similarity Score 0.51
HY-147796EGFR/HER2/CDK9-IN-1 -
Similarity Score 0.50
HY-147779VEGFR-2-IN-20 -
Similarity Score 0.50
HY-122883BC-1471 -
Similarity Score 0.50
HY-N12179Brevianamide M -
Similarity Score 0.50
HY-147798EGFR/HER2/CDK9-IN-3 -
Similarity Score 0.48
HY-147794CDK9-IN-41 -
Similarity Score 0.48
HY-128132C3a receptor agonist 1 -
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