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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
15 Results for "
Epothilones
" in MedChemExpress (MCE) Product Catalog:
Products (15)
15 Results for "Epothilones" in MCE Product Catalog:
8
Epothilone B is a microtubule stabilizer (MSA) with a Ki of 0.71μM, and is a MSA with blood-brain barrier permeability. Epothilone B acts by binding to the αβ-tubulin heterodimer subunit which causes decreasing of αβ-tubulin dissociation .
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Target:
Utidelone (Epothilone D) is a potent microtubule stabilizer.
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Category:
Microorganisms Macrolide Antibiotics Antibiotics Disease Research Anticancer Disease Research Fields Cancer
Target:
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研究分野:
Epothilone F is a 16-membered macrolide microtubule-targeting agent. Epothilone F exhibits significant anticancer activity, and it particularly exerts effective inhibitory effects on paclitaxel-resistant cancer cells. Epothilone F inhibits the proliferation of breast cancer cells, non-small cell lung cancer cells and drug-resistant ovarian cancer cells, and it has been widely used in cancer-related research .
別名: 21-Aminoepothilone B
BMS 310705 (21-Aminoepothilone B) is an analog of Epothilone B (HY-17029), targeting to malignancies such as ovarian, renal, bladder, and lung carcinoma. BMS 310705 induces significant apoptosis via mitochondrial-mediated pathway .
製品番号: HY-15278A
純度: 95.11%
別名: (16R)-Epothilone D; (16R)-UTD1; (16R)-KOS 862
Target:
(16R)-Utidelone ((16R)-Epothilone D) is the isomer of Utidelone (HY-15278), and can be used as an experimental control. Utidelone (KOS 862) is a potent microtubule stabilizer.
製品番号: HY-100710
CAS 番号: 186692-73-9
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研究分野:
Epothilone C is a polyketide natural product. Epothilone C is produced by the combined action of one nonribosomal peptide synthetase (NRPS) and nine polyketide synthase (PKS) modules in a multienzyme system. Epothilone C can be used for tumor research .
製品番号: HY-147317
CAS 番号: 201049-37-8
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研究分野:
Epothilone E is a related compound of epothilone, which inhibits microtubule protein function and blocks cell division, and has anti-tumor activity .
製品番号: HY-107090
CAS 番号: 252981-48-9
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研究分野:
ABJ-879 is an Epothilone (HY-15278) derivative. ABJ-879 targets tubulin and can be used for the research of cancer .
製品番号: HY-13657
CAS 番号: 220889-57-6
別名: KOS-1584
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研究分野:
cis-9,10-Dehydroepothilone D (KOS-1584) is an epothilone derivative with antiproliferative activity and tubulin polymerization activity. cis-9,10-Dehydroepothilone D can be used for the study of lung cancer, colon cancer, prostate cancer and breast cancer .
製品番号: HY-13503R
CAS 番号: 152044-53-6
別名: Epo A (Standard)
製品番号: HY-17029R
CAS 番号: 152044-54-7
別名: EPO 906 (Standard); Patupilone (Standard)
Epothilone B (Standard) is the analytical standard of Epothilone B. This product is intended for research and analytical applications. Epothilone B is a microtubule stabilizer with a Ki of 0.71μM. It acts by binding to the αβ-tubulin heterodimer subunit which causes decreasing of αβ-tubulin dissociation.
製品番号: HY-W754654
製品番号: HY-15278R
CAS 番号: 189453-10-9
別名: Epothilone D (Standard); UTD1 (Standard); KOS 862 (Standard)
Utidelone (Standard) (Epothilone D (Standard)) is the analytical standard ofUtidelone. This product is intended for research and analytical applications. Utidelone is a potent microtubule stabilizer .
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研究分野:
Cintriamide (Cintramide) (Compound 5) is a key intermediate for the synthesis of photoswitchable epothilone-based microtubule stabiliser .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
