1 Result for "

FGFR-IN-10

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "FGFR-IN-10" in MCE Product Catalog:

Cat. No.: HY-148597
CAS No.: 2847092-41-3
Target:  

FGFR Cytochrome P450

Research Areas:  

Cancer

FGFR-IN-10 is an orally active inhibitor of FGFR and Cytochrome P450 (CYPs). FGFR-IN-10 inhibits wide type and V564F mutant FGFR2 with IC50s of 104.1 nM and 43.6 nM, respectively. FGFR-IN-10 also inhibits CYPs with IC50s of 3.33 μM (CYP2C9), 18.75 μM (CYP2C19), 4.34 μM (CYP2CD6), and 0.69 μM (CYP3A4), respectively .
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