24 Results for "

Ferulate

" in MedChemExpress (MCE) Product Catalog:
Products (24)

24 Results for "Ferulate" in MCE Product Catalog:

3
Ethyl ferulate
Ethyl ferulate
0 Images
3 Cited Publications
Cat. No.: HY-N0061
CAS No.: 4046-02-0
Category:  

Monophenols Simple Phenylpropanols Phenols Dicerothamnus rhinocerotis Phenylpropanoids Plants Umbelliferae

Target:  

Reactive Oxygen Species (ROS)

Ethyl ferulate, a naturally lipophilic derivative of ferulic acid originally derived from Rhizoma Chuanxiong, induces heme oxygenase-1 (HO-1) and protects rat neurons against oxidative stress . Ethyl ferulate also protects neurons against amyloid β peptide (1-42)-induced oxidative stress and neurotoxicity .
1
Ferulic acid methyl ester
Ferulic acid methyl ester
0 Images
1 Cited Publications
Cat. No.: HY-W018643
CAS No.: 2309-07-1
Synonyms: Methyl Ferulate
Category:  

Monophenols Neurological Disease Stemonaceae Simple Phenylpropanols Phenols Phenylpropanoids Plants Disease Research Fields Stemona tuberosa Lour. Cancer

Target:  

p38 MAPK Autophagy

Ferulic acid methyl ester (Methyl ferulate) is a derivative of ferulic acid, isolated from Stemona tuberosa, with anti-inflammatory and antioxidant properties . Ferulic acid methyl ester is a cell membrane and brain permeable compound, shows free radical scavenging ability, used in the research of neurodegenerative disorders . Ferulic acid methyl ester inhibits COX-2 expression, blocks p-p38 and p-JNK in primary bone marrow derived-macrophages .
1
Coniferyl ferulate
Coniferyl ferulate
0 Images
1 Cited Publications
Cat. No.: HY-N1916
CAS No.: 63644-62-2
Category:  

Simple Phenylpropanols Phenols Polyphenols Dicerothamnus rhinocerotis Phenylpropanoids Plants Umbelliferae Disease Research Fields Cancer

Target:  

Glutathione S-transferase P-glycoprotein Apoptosis iGluR CaMK p38 MAPK Reactive Oxygen Species (ROS) Bacterial

Coniferyl ferulate is an orally active phenolic acid compound. Coniferyl ferulate is a potent inhibitor of glutathione S-transferase (GST) (IC50 = 0.3 μM), which downregulates P-gp expression, induces apoptosis in B-MD-C1 (ADR+/+) cells, and reverses multidrug resistance. Coniferyl ferulate blocks the NMDAR/NR2B-CaMKII-MAPKs signaling pathway, inhibits ROS production and mitochondrial apoptosis, while reshapes the intestinal microbiota and microbial metabolism, ameliorates colonic inflammation and alleviates depressive symptoms in mice. Coniferyl ferulate can alleviate the toxicity of xylene to hematopoietic stem and progenitor cells by targeting Mgst2. Coniferyl ferulate exhibits antibacterial activity against the Gram-positive Bacillus subtilis and Staphylococcus aureus .
1
Cycloartenyl ferulate
Cycloartenyl ferulate
0 Images
1 Cited Publications
Cat. No.: HY-125938
CAS No.: 21238-33-5
Purity:  98.98%
Synonyms: Cycloartenol Ferulate; Cycloartenol ferulic acid ester
Category:  

Triterpenes other families Monophenols Terpenoids Phenols Plants Disease Research Fields Inflammation/Immunology

Target:  

Drug Derivative Apoptosis Reactive Oxygen Species (ROS) JAK STAT

Cycloartenyl ferulate (Cycloartenol ferulate; Cycloartenol ferulic acid ester) is a derivative of γ-oryzanol (HY-B2194) with multiple biological activities including antioxidant, anti-inflammatory, and anti-tumor properties. Cycloartenyl ferulate selectively binds to IFNγR1 (binding affinity Kd = 0.5 μM) to activate the canonical JAK1/2-STAT1 signaling pathway. Cycloartenyl ferulate inhibits paraquat (PQ)-triggered apoptosis and ROS in HK2 cells. Cycloartenyl ferulate enhances the activation and cytolytic activity of natural killer (NK) cells by upregulating the expression of NK cell activation receptors (NKG2D, NKp30, NKp44) and the release of cytotoxic molecules and cytokine IFNγ. Cycloartenyl ferulate exerts anti-cancer effects in tumor mice models. Cycloartenyl ferulate can be used for the study of cancer and allergic inflammation intervention .
Phenethyl ferulate
Phenethyl ferulate
0 Images
Cat. No.: HY-W009248
CAS No.: 71835-85-3
Category:  

Monophenols Phenols Plants Umbelliferae Kleinia odora (Forssk.) DC. Disease Research Fields Inflammation/Immunology

Target:  

COX Lipoxygenase

Phenethyl ferulate is a major constituent ofQianghuo, shows inhibitory activity against cyclooxygenase (COX) and 5-lipoxygenase (5-LOX) with IC50 values of 4.35 μM and 5.75 μM, respectively .
24-Methylenecycloartanyl ferulate
24-Methylenecycloartanyl ferulate
0 Images
Cat. No.: HY-N8122
CAS No.: 469-36-3
Category:  

Triterpenes other families Monophenols Terpenoids Phenols Plants Disease Research Fields Cancer

Target:  

Akt

24-Methylenecycloartanyl ferulate is a γ-oryzanol compound. 24-Methylenecycloartanyl ferulate promotes parvin-beta expression in human breast cancer cells. 24-Methylenecycloartanyl ferulate is a potential ATP-competitive Akt1 inhibitor (EC50= 33.3μM) .
Isopropyl ferulate
Isopropyl ferulate
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Cat. No.: HY-N4203
CAS No.: 59831-94-6
Category:  

Infection Monophenols Simple Phenylpropanols Phenols Phenylpropanoids Plants Umbelliferae Kleinia odora (Forssk.) DC. Disease Research Fields

Target:  

Fungal

Isopropyl ferulate, isolated from Notopterygium incisum, is used in the reduction of pharmaceuticals, preparation of antifungal agents, cosmetics and as antioxidant agent and so forth .
(E)-Ferulic acid methyl ester
(E)-Ferulic acid methyl ester
0 Images
Cat. No.: HY-W018643A
CAS No.: 22329-76-6
Synonyms: Methyl (E)-Ferulate
Category:  

Monophenols Ginkgoaceae Simple Phenylpropanols Other Diseases Phenols Phenylpropanoids Plants Disease Research Fields Ginkgo biloba

Target:  

COX

(E)-Ferulic acid methyl ester (Methyl (E)-ferulate) exhibits strong DPPH and ABTS + radical scavenging activities .
Campesteryl ferulate
Campesteryl ferulate
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Cat. No.: HY-W749362
CAS No.: 20972-07-0
Category:  

Gramineae Oryza sativa L. Plants Steroids

Target:  

Drug Derivative

Campesteryl ferulate is a component of γ-Oryzanol (HY-B2194). Campesteryl ferulate can be extracted from rice bran .
p-Hydroxyphenethyl trans-ferulate
p-Hydroxyphenethyl trans-ferulate
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Cat. No.: HY-N3078
CAS No.: 84873-15-4
Category:  

Simple Phenylpropanols Phenols Polyphenols Phenylpropanoids Plants Umbelliferae Disease Research Fields Endocrinology Echinacea angustifolia DC.

Target:  

Glycosidase

p-Hydroxyphenethyl trans-ferulate has anti-hyperglycemic (yeast α-glucosidase, IC50=19.24 ± 1.73 µM), antioxidant, and anti-inflammatory activities . p-Hydroxyphenethyl trans-ferulate shows inhibiting anticancer and serotonergic activity .
Eicosyl ferulate
Eicosyl ferulate
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Cat. No.: HY-N8490
CAS No.: 133882-79-8
Category:  

Aristolochia zollingeriana Miq. Monophenols Metabolic Disease Phenols Plants Disease Research Fields Aristolochiaceae

Target:  

Others

Eicosyl ferulate, a phenolic compound, is isolated from the fresh root and stem of Aristolochia kankauensis. Eicosyl ferulate exhibits glucose uptake stimulatory activity .
Hexacosyl (E)-ferulate
Hexacosyl (E)-ferulate
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Cat. No.: HY-N4046
CAS No.: 63034-29-7
Synonyms: n-Hexacosyl trans-Ferulate
Category:  

Monophenols Dendranthema morifolium (Ramat.) Tzvel. Phenols Plants Compositae

Target:  

Others

Hexacosyl (E)-ferulate (n-Hexacosyl trans-ferulate) is an antioxidant agent that displays significant antioxidant activity in the DPPH (HY-112053) assay with the RC50 (50% reduction concentration) of 0.0976 mg/mL .
Erythrinasinate B
Erythrinasinate B
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Cat. No.: HY-N3160
CAS No.: 101959-37-9
Synonyms: Octacosyl (E)-Ferulate
Category:  

Monophenols Phenols Plants Erythrina caffra Thunb. Fabaceae

Target:  

Parasite

Octacosyl (E)-ferulate (Erythrinasinate B) (Compound 1) is an antiplasmodial compound. Octacosyl (E)-ferulate can be isolated from Erythrina .
Ethyl (E)-ferulate
Ethyl (E)-ferulate
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Cat. No.: HY-W590845
CAS No.: 28028-62-8
Target:  

AMPK Keap1-Nrf2

Research Areas:  

Neurological Disease Inflammation/Immunology

Ethyl (E)-ferulate is an AMPK/Nrf2 signaling pathway activator that can reduce lipopolysaccharide (HY-D1056)-induced acute lung injury. Additionally, Ethyl (E)-ferulate exhibits free radical scavenging properties, providing anti-inflammatory, antioxidant, neuroprotective, and sunscreen effects. Ethyl (E)-ferulate holds promise for research in the fields of inflammation and neurodegenerative diseases .
Docosyl trans-ferulate
Docosyl trans-ferulate
0 Images
Cat. No.: HY-W707365
CAS No.: 101927-24-6
Category:  

Monophenols Zingiber mekongense Gagnep. Phenols Plants Zingiberaceae

Target:  

HIV

Docosyl trans-ferulate (compound 2) is an antiviral compound. Docosyl trans-ferulate exhibits anti-HIV-1 activity in anti-syncytial assays using the ΔTat/revMC99 virus and 1A2 cell line systems .
(-)-Bornyl ferulate
(-)-Bornyl ferulate
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Cat. No.: HY-W706470
CAS No.: 55511-07-4
Category:  

Monophenols Phenols Plants Umbelliferae Kleinia odora (Forssk.) DC.

Target:  

Lipoxygenase COX

(-)-Bornyl ferulate is a 5-lipoxygenase and COX inhibitor with IC50s of 10.4 μM and 12.0 μM, respectively .
Geranyl ferulate
Geranyl ferulate
0 Images
Cat. No.: HY-N9092
CAS No.: 1206615-69-1
Synonyms: (E)-geranylferulic acid
Category:  

Zingiber officinale Roscoe Monophenols Simple Phenylpropanols Phenols Phenylpropanoids Plants Disease Research Fields Inflammation/Immunology Zingiberaceae

Target:  

NO Synthase

Geranyl ferulate ((E)-geranylferulic acid), isolated from Zingiber officinale, exhibits inhibitory effect on the production of nitric oxide (NO) .
(E)-Benzyl ferulate
(E)-Benzyl ferulate
0 Images
Cat. No.: HY-134607
CAS No.: 132335-97-8
Synonyms: Benzyl (E)-p-coumarate
Category:  

Animals Simple Phenylpropanols Phenylpropanoids

Target:  

Others

(E)-Benzyl ferulate is a phenolic ester that can be isolated from Thai propolis .
24-Methylcholesterol
24-Methylcholesterol
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Cat. No.: HY-N12467
CAS No.: 23929-42-2
Category:  

Triterpenes Microorganisms Terpenoids

Target:  

Others

24-Methylcholesterol is a trans-ferulate ester that can be isolated from rice bran. 24-Methylcholesterol significantly inhibited TPA-induced inflammation .
Methyl (Z)-ferulate
Methyl (Z)-ferulate
0 Images
Cat. No.: HY-N16424
CAS No.: 34298-89-0
Synonyms: Me cis-Ferulate; cis-Ferulic acid methyl ester
Category:  

Monophenols Phenols Aizoaceae Plants Tetragonia tetragonioides (Pall.) Kuntze

Target:  

Fungal

Methyl (Z)-ferulate (Me cis-ferulate) (cis-Ferulic acid methyl ester) is an endogenous Germination self-inhibitor. Methyl (Z)-ferulate can be isolated from the leaves of Tetragonia tetragonoides. Methyl (Z)-ferulate blocks uredospores germination in rust fungi by reversibly inhibiting the digestion of the germination pore plug through the regulation of pre-existing enzyme activity. Methyl (Z)-ferulate also has antioxidant activity, effectively scavenging DPPH and ABTS + radical .
Assay Types