4046-02-0
Chemical Structure
Ethyl ferulate
- CAS No.: 4046-02-0
- Formula:C12H14O4
- Molecular Weight:222.24
IUPAC Name: ethyl (E)-3-(4-hydroxy-3-methoxyphenyl)acrylate
InChIKey: ATJVZXXHKSYELS-FNORWQNLSA-N
SMILES: O=C(OCC)/C=C/C1=CC=C(O)C(OC)=C1
Biological Activity: Ethyl ferulate, a naturally lipophilic derivative of ferulic acid originally derived from Rhizoma Chuanxiong, induces heme oxygenase-1 (HO-1) and protects rat neurons against oxidative stress[1]. Ethyl ferulate also protects neurons against amyloid β peptide (1-42)-induced oxidative stress and neurotoxicity[2].
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Ethyl ferulate | 99.85% | Ethyl ferulate, a naturally lipophilic derivative of ferulic acid originally derived from Rhizoma Chuanxiong, induces heme oxygenase-1 (HO-1) and protects rat neurons against oxidative stress. Ethyl ferulate also protects neurons against amyloid β peptide (1-42)-induced oxidative stress and neurotoxicity. | ||||||||||||||||||||
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- [1]. Scapagnini G, et al. Ethyl ferulate, a lipophilic polyphenol, induces HO-1 and protects rat neurons against oxidative stress. Antioxid Redox Signal. 2004 Oct;6(5):811-8. [Content Brief]
- [2]. Sultana R, et al. Ferulic acid ethyl ester protects neurons against amyloid beta- peptide(1-42)-induced oxidative stress and neurotoxicity: relationship to antioxidant activity. J Neurochem. 2005 Feb;92(4):749-58. [Content Brief]
Keywords