24-Methylenecycloartanyl ferulate

Cat. No.: HY-N8122 Purity: 98.05%: FAQs
Data Sheet SDS COA Handling Instructions

24-Methylenecycloartanyl ferulate is a γ-oryzanol compound. 24-Methylenecycloartanyl ferulate promotes parvin-beta expression in human breast cancer cells. 24-Methylenecycloartanyl ferulate is a potential ATP-competitive Akt1 inhibitor (EC₅₀= 33.3μM).

For research use only. We do not sell to patients.

24-Methylenecycloartanyl ferulate Chemical Structure

CAS No. : 469-36-3

Size	Price	Stock	Quantity
5 mg	USD 390	In-stock	Estimated Time of Arrival: December 31
10 mg	USD 690	In-stock	Estimated Time of Arrival: December 31
50 mg		Get quote
100 mg		Get quote

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Biological Activity
Purity & Documentation
References
Customer Review

Description

IC₅₀ & Target

Akt1

33.3 μM (EC₅₀)

Molecular Weight

616.91

Appearance

Solid

Formula

C₄₁H₆₀O₄

CAS No.

469-36-3

SMILES

CC1(C)[[email protected]@H](OC(/C=C/C2=CC=C(O)C(OC)=C2)=O)CC[[email protected]]3(C4)C54CC[[email protected]]6(C)[[email protected]@H]([[email protected]](C)CCC(C(C)C)=C)CC[[email protected]](C)6[[email protected]]5([H])CC[[email protected]@]13[H]

Structure Classification

Source

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

4°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

Solvent & Solubility

In Vitro:

DMSO : ≥ 12.5 mg/mL (20.26 mM)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	1.6210 mL	8.1049 mL	16.2098 mL
5 mM	0.3242 mL	1.6210 mL	3.2420 mL
10 mM	0.1621 mL	0.8105 mL	1.6210 mL

*Please refer to the solubility information to select the appropriate solvent.

In Vivo:

1.

Add each solvent one by one: 10% DMSO 90% corn oil
Solubility: ≥ 1.25 mg/mL (2.03 mM); Clear solution

*All of the co-solvents are available by MCE.

Purity & Documentation

Purity: 98.05%

Select Batch:

Data Sheet (271 KB) SDS (251 KB)

COA (247 KB) HNMR (153 KB) CNMR (181 KB) RP-HPLC (450 KB) MS (189 KB)

Handling Instructions (2659 KB)

References

[1]. Heon Woong Kim, et al. 24-Methylenecycloartanyl ferulate, a major compound of γ-oryzanol, promotes parvin-beta expression through an interaction with peroxisome proliferator-activated receptor-gamma 2 in human breast cancer cells. Biochem Biophys Res Comm [Content Brief]

Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Molarity Calculator
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The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

The dilution calculator equation

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Keywords:

24-Methylenecycloartanyl ferulate469-36-3AktPKBProtein kinase Bparvin-betaexpressionperoxisomeproliferator-activatedreceptorPPARbreastcancerInhibitorinhibitorinhibit

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