1. PI3K/Akt/mTOR
    Apoptosis
  2. Akt
    Apoptosis
  3. FPA-124

FPA-124 

Cat. No.: HY-15369
Handling Instructions

FPA-124 is a cell-permeable copper complex and a selective Akt inhibitor. FPA-124 interacts with both the pleckstrin homology (PH) and the kinase domains of Akt. FPA-124 induces apoptosis.

For research use only. We do not sell to patients.

FPA-124 Chemical Structure

FPA-124 Chemical Structure

CAS No. : 902779-59-3

Size Price Stock Quantity
10 mM * 1 mL in DMSO USD 253 In-stock
Estimated Time of Arrival: December 31
1 mg USD 100 In-stock
Estimated Time of Arrival: December 31
5 mg USD 300 In-stock
Estimated Time of Arrival: December 31
10 mg USD 500 In-stock
Estimated Time of Arrival: December 31
50 mg   Get quote  
100 mg   Get quote  

* Please select Quantity before adding items.

Customer Review

Based on 1 publication(s) in Google Scholar

Top Publications Citing Use of Products

View All Akt Isoform Specific Products:

  • Biological Activity

  • Purity & Documentation

  • References

  • Customer Review

Description

FPA-124 is a cell-permeable copper complex and a selective Akt inhibitor. FPA-124 interacts with both the pleckstrin homology (PH) and the kinase domains of Akt. FPA-124 induces apoptosis[1][2].

In Vitro

FPA-124 exhibits dose-dependent growth inhibitory effects with IC50s of 7, 10, 34, and 55 μM in BT20, PC-3, COLO 357 and BxPC-3 Cancer cell lines, respectively[1].

Molecular Weight

382.73

Formula

C₁₁H₁₀Cl₂CuN₃O₂S

CAS No.

902779-59-3

SMILES

O=C1C2=CC=CC=C2OC=C1/C=[N]3[Cu]([Cl-])(S=C(N)N\3)[Cl-].[2+]

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

References
  • No file chosen (Maximum size is: 1024 Kb)
  • If you have published this work, please enter the PubMed ID.
  • Your name will appear on the site.
  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

Your Recently Viewed Products:

Inquiry Online

Your information is safe with us. * Required Fields.

Product name

 

Salutation

Applicant name *

 

Email address *

Phone number *

 

Organization name *

Country or Region *

 

Requested quantity *

Remarks

Bulk Inquiry

Inquiry Information

Product name:
FPA-124
Cat. No.:
HY-15369
Quantity:
MCE Japan Authorized Agent: