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  3. GSK2110183 analog 1 hydrochloride

GSK2110183 analog 1 hydrochloride 

Cat. No.: HY-15966A Purity: 99.39%
Handling Instructions

GSK2110183 analog 1 hydrochloride is the structural analogue of GSK2110183.

For research use only. We do not sell to patients.

GSK2110183 analog 1 hydrochloride Chemical Structure

GSK2110183 analog 1 hydrochloride Chemical Structure

CAS No. : 2070009-64-0

Size Price Stock Quantity
10 mM * 1 mL in DMSO USD 462 In-stock
Estimated Time of Arrival: December 31
5 mg USD 420 In-stock
Estimated Time of Arrival: December 31
10 mg USD 600 In-stock
Estimated Time of Arrival: December 31
50 mg USD 1800 In-stock
Estimated Time of Arrival: December 31
100 mg USD 2520 In-stock
Estimated Time of Arrival: December 31
200 mg   Get quote  
500 mg   Get quote  

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Customer Review

Based on 3 publication(s) in Google Scholar

Other Forms of GSK2110183 analog 1 hydrochloride:

Top Publications Citing Use of Products

Publications Citing Use of MCE GSK2110183 analog 1 hydrochloride

    GSK2110183 analog 1 hydrochloride purchased from MCE. Usage Cited in: Theranostics. 2019 Jan 30;9(4):1096-1114.

    RAS signaling alterations induced by the AKT inhibitor GSK2110183 (10 nM; 8 h), showing that AKT signaling is mutually suppressive.

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    Description

    GSK2110183 analog 1 hydrochloride is the structural analogue of GSK2110183.

    Molecular Weight

    481.77

    Formula

    C₁₈H₁₇Cl₃F₂N₄OS

    CAS No.

    2070009-64-0

    SMILES

    O=C(C1=CC(C2=C(Cl)C=NN2C)=C(Cl)S1)N[[email protected]@H](CC3=CC=C(F)C(F)=C3)CN.[H]Cl

    Shipping

    Room temperature in continental US; may vary elsewhere.

    Storage
    Powder -20°C 3 years
    4°C 2 years
    In solvent -80°C 6 months
    -20°C 1 month
    Solvent & Solubility
    In Vitro: 

    DMSO : 100 mg/mL (207.57 mM; Need ultrasonic)

    Preparing
    Stock Solutions
    Concentration Solvent Mass 1 mg 5 mg 10 mg
    1 mM 2.0757 mL 10.3784 mL 20.7568 mL
    5 mM 0.4151 mL 2.0757 mL 4.1514 mL
    10 mM 0.2076 mL 1.0378 mL 2.0757 mL
    *Please refer to the solubility information to select the appropriate solvent.
    In Vivo:
    • 1.

      Add each solvent one by one:  10% DMSO    40% PEG300    5% Tween-80    45% saline

      Solubility: ≥ 2.5 mg/mL (5.19 mM); Clear solution

    • 2.

      Add each solvent one by one:  10% DMSO    90% (20% SBE-β-CD in saline)

      Solubility: ≥ 2.5 mg/mL (5.19 mM); Clear solution

    • 3.

      Add each solvent one by one:  10% DMSO    90% corn oil

      Solubility: ≥ 2.5 mg/mL (5.19 mM); Clear solution

    • 4.

      Add each solvent one by one:  10% DMSO    90% saline

      Solubility: ≥ 2.5 mg/mL (5.19 mM); Clear solution

    *All of the co-solvents are provided by MCE.
    Animal Administration

    MCE has not independently confirmed the accuracy of these methods. They are for reference only.

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    • Molarity Calculator

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    Keywords:

    GSK2110183 analog 1AktPKBProtein kinase BInhibitorinhibitorinhibit

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    Product Name:
    GSK2110183 analog 1 hydrochloride
    Cat. No.:
    HY-15966A
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