3 Results for "

GH4C1 cells

" in MedChemExpress (MCE) Product Catalog:
Products (3)

3 Results for "GH4C1 cells" in MCE Product Catalog:

Cat. No.: HY-107678
CAS No.: 874450-44-9
Purity:  98.45%
Synonyms: WAY-317538
Target:  

nAChR

Research Areas:  

Neurological Disease

SEN 12333 (WAY-317538) is a potent, selective and orally active α7 nAChR agonist. SEN12333 displays high affinity for the rat α7 nAChRs expressed in GH4C1 cells (K>i=260 nM) and acts as full agonist in functional Ca 2+ flux studies (EC50=1.6 μM). SEN 12333 is used for AD and schizophrenia research .
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Cat. No.: HY-107678R
CAS No.: 874450-44-9
Synonyms: WAY-317538 (Standard)
Research Areas:  

Neurological Disease

SEN12333 (Standard) is the analytical standard of SEN12333 (HY-107678). This product is intended for research and analytical applications. SEN 12333 (WAY-317538) is a potent, selective and orally active α7 nAChR agonist. SEN12333 displays high affinity for the rat α7 nAChRs expressed in GH4C1 cells (K>i=260 nM) and acts as full agonist in functional Ca2+ flux studies (EC50=1.6 μM). SEN 12333 is used for AD and schizophrenia research .
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Cat. No.: HY-12153
CAS No.: 929562-28-7
Target:  

Cholinesterase (ChE)

Research Areas:  

Neurological Disease

JNJ-1930942 is a selective and blood-brain barrier (BBB) penetrant α(7) nAChR positive allosteric modulator.JNJ-1930942 enhances the Choline (HY-B0282)-evoked rise in intracellular Ca 2+ levels and neurotransmission at hippocampal dentate gyrus synapses. JNJ-1930942 reverses the naturally occurring sensory gating deficit in DBA/2 mice .
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