874450-44-9
874450-44-9
Chemical Structure
SEN12333
Synonym(s): WAY-317538
- CAS No.: 874450-44-9
- Formula:C20H25N3O2
- Molecular Weight:339.43
IUPAC Name: 5-morpholino-N-(4-(pyridin-3-yl)phenyl)pentanamide
InChIKey: XCHIZTUBUXZESJ-UHFFFAOYSA-N
SMILES: O=C(CCCCN1CCOCC1)NC2=CC=C(C3=CN=CC=C3)C=C2
Biological Activity: SEN 12333 (WAY-317538) is a potent, selective and orally active α7 nAChR agonist. SEN12333 displays high affinity for the rat α7 nAChRs expressed in GH4C1 cells (K>i=260 nM) and acts as full agonist in functional Ca2+ flux studies (EC50=1.6 μM). SEN 12333 is used for AD and schizophrenia research[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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SEN12333 | 98.45% | SEN 12333 (WAY-317538) is a potent, selective and orally active α7 nAChR agonist. SEN12333 displays high affinity for the rat α7 nAChRs expressed in GH4C1 cells (K>i=260 nM) and acts as full agonist in functional Ca2+ flux studies (EC50=1.6 μM). SEN 12333 is used for AD and schizophrenia research. | ||||||||||||||||||||
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SEN12333 (Standard) | ≥98% | SEN12333 (Standard) is the analytical standard of SEN12333 (HY-107678). This product is intended for research and analytical applications. SEN 12333 (WAY-317538) is a potent, selective and orally active α7 nAChR agonist. SEN12333 displays high affinity for the rat α7 nAChRs expressed in GH4C1 cells (K>i=260 nM) and acts as full agonist in functional Ca2+ flux studies (EC50=1.6 μM). SEN 12333 is used for AD and schizophrenia research. | ||||||||||||||||||||
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References
Keywords
