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GSK3A/B

" in MedChemExpress (MCE) Product Catalog:

By Targets:	FGFR (1) LIM Kinase (LIMK) (1) MAP3K (1) Ribosomal S6 Kinase (RSK) (1) Src (1)
By Research Areas:	Cancer (1)

Inhibitors & Agonists

Antibodies

Targets Recommended: GSK-3

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-136848

SM1-71	MAP3K Src FGFR Ribosomal S6 Kinase (RSK) LIM Kinase (LIMK)	Cancer
SM1-71 (compound 5) is a potent TAK1 inhibitor, with a K_i of 160 nM, it also can covalently inhibit MKNK2, MAP2K1/2/3/4/6/7, GAK, AAK1, BMP2K, MAP3K7, MAPKAPK5, *GSK3A/B, MAPK1/3, SRC, YES1, FGFR1, ZAK (MLTK), MAP3K1, LIMK1* and RSK2. SM1-71 can inhibit proliferation of multiple cancer cell lines .

Host:	Rabbit (4)
Reactivity:	Human (2) Rat (4) Mouse (4)
Application:	IHC-P (2) ICC/IF (2) IP (3) WB (4) ELISA (1)
Isotype:	IgG (3) IgG/Kappa (1)
Conjugation:	Non-conjugated (4)
Clonality:	Monoclonal (3) Recombinant (1)
Modification:	Phosphorylated (2) Unmodified (1)

Cat. No.	Compare	Product Name	Application	Reactivity	Image

HY-P86437

	GSK3 alpha+beta Antibody (YA6129) GSK3A; Glycogen synthase kinase-3 alpha; GSK-3 alpha; Serine/threonine-protein kinase GSK3A; GSK3B; Glycogen synthase kinase-3 beta; GSK-3 beta; Serine/threonine-protein kinase GSK3B	WB, IHC-P, ICC/IF, IP, ELISA	Human, Mouse, Rat
	GSK3 alpha+beta Antibody (YA6129) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to GSK3 alpha+beta.

HY-P86164

	*Phospho-GSK3 alpha+beta(Tyr216/Tyr279) (YA5856)* GSK3A; Glycogen synthase kinase-3 alpha; GSK-3 alpha; Serine/threonine-protein kinase GSK3A; GSK3B; Glycogen synthase kinase-3 beta; GSK-3 beta; Serine/threonine-protein kinase GSK3B	WB, IHC-P, ICC/IF	Human, Mouse, Rat
	Phospho-GSK3 alpha+beta(Tyr216/Tyr279) Antibody (YA5856) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Phospho-GSK3 alpha+beta(Tyr216/Tyr279).

HY-P80819

	*Phospho-GSK3 (Tyr216/Tyr279) Antibody (YA194)* 1 Publications Verification Serine/threonine-protein kinase GSK3A; Serine/threonine-protein kinase GSK3B	WB, IP	Mouse, Rat
	Phospho-GSK3 (Tyr216/Tyr279) Antibody (YA194) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Phospho-GSK3 (Tyr216/Tyr279).

HY-P80819A

	*Phospho-GSK3 (Tyr216/Tyr279) Antibody (YA194)(PBS only)* Serine/threonine-protein kinase GSK3A; Serine/threonine-protein kinase GSK3B	WB, IP	Mouse, Rat
	Phospho-GSK3 (Tyr216/Tyr279) Antibody (YA194) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Phospho-GSK3 (Tyr216/Tyr279).

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BODIPY 493/503 purchased from MedChemExpress. Usage Cited in: Nat Commun. 2025 Feb 1;16(1):1241. [Abstract]

MedchemExpress Validation 01

Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature. Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature. Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature.

BODIPY 493/503 purchased from MedChemExpress. Usage Cited in: Nat Commun. 2025 Feb 1;16(1):1241. [Abstract]

MedchemExpress Validation 01

MedchemExpress Validation 03

Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred

MedchemExpress Validation 04

MedchemExpress Validation

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