84 Results for "

GpC

" in MedChemExpress (MCE) Product Catalog:
Products (84)

84 Results for "GpC" in MCE Product Catalog:

3
3 Cited Publications
Cat. No.: HY-17552
CAS No.: 28319-77-9
Synonyms: Choline Alfoscerate; Alpha-GpC; L-α-GpC
sn-Glycero-3-phosphocholine (Choline Alfoscerate) is a precursor in the biosynthesis of brain phospholipids and increases the bioavailability of choline in nervous tissue. sn-Glycero-3-phosphocholine (Choline Alfoscerate) has significant effects on cognitive function with a good safety profile and tolerability, and is effective in the treatment of Alzheimer's disease and dementia .
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1
1 Cited Publications
Cat. No.: HY-P99013
CAS No.: 1365267-33-9
Synonyms: GC33; RO5137382

Target:  

Glycoprotein VI

Research Areas:  

Cancer

Codrituzumab (GC33) is a humanized monoclonal antibody targeting human GPC3 (glypican-3), with high affinity (Kd of 0.673 nM). GPC3 is an oncofetal protein expressed on the cell surface of hepatocellular carcinoma (HCC). Codrituzumab induces antibody-dependent cellular cytotoxicity (ADCC) and inhibits tumor growth .
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1
1 Cited Publications
Cat. No.: HY-P70487
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: Glypican-3; GTR2-2; Intestinal protein OCI-5; MXR7; GpC3; OCI5
Species:  
Source:  
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Cat. No.: HY-153360
CAS No.: 2873460-70-7
Purity:  98.99%
Research Areas:  

Cancer

MC-GGFG-AM-(10Me-11F-Camptothecin) is a linker-payload conjugate used to synthesize ZW251. ZW251 an antibody-drug conjugate (ADC) targeting human GPC3. ZW251 consists of a humanized IgG1 antibody conjugated to a novel camptothecin-based topoisomerase 1 inhibitor, ZD06519, via a linker. The linker is the maleimide anchor and a glycyl glycyl phenylalanyl glycine (GGFG)-aminomethyl (AM) cleavable linker. ZW251 has high affinity with human and cynomolgus monkey GPC3. ZW251 displays rapid internalization in GPC3-expressing HCC cell lines, and bystander-mediated killing of GPC3 negative cancer cells .
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Cat. No.: HY-W1124925
CAS No.: 3066439-94-6
DOTA-GPC3 targeting peptide 2 (Sequence 30) is a RDC peptide targeting GPC3, with Kd of 0.3 nM. DOTA-GPC3 targeting peptide 2 is composed of DOTA and GPC3 targeting peptide 2. DOTA-GPC3 targeting peptide 2 can be labeled with radioactive elements .
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Cat. No.: HY-P10888A
Target:  

Glycoprotein VI

Research Areas:  

Cancer

GPC3 targeting peptide 1 TFA is a GPC3 targeting peptide, with a Kd value of 0.23 nM .
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Cat. No.: HY-P990841

Target:  

Glycoprotein VI

Research Areas:  

Cancer

Anti-pan-Glypican Antibody (HS20) is a kind of human IgG1 κ human antibody, targeting to human pan-Glypican. Anti-pan-Glypican Antibody (HS20) can neutralize the heparan sulfate (HS) chains on GPC3 thereby disrupting the Wnt3a-GPC3 interactions leading to blockade of the Wnt3a/β-catenin signaling. Anti-pan-Glypican Antibody (HS20) can be used for the research of cancer, such as hepatocellular carcinoma (HCC) .
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Cat. No.: HY-P10888
CAS No.: 3066113-41-2
Target:  

Glycoprotein VI

Research Areas:  

Cancer

GPC3 targeting peptide 1 is a GPC3 targeting peptide, with a Kd value of 0.23 nM .
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Cat. No.: HY-P990840

Target:  

Glycoprotein VI

Research Areas:  

Cancer

Anti-GPC3 Antibody (YP7) is a kind of mouse IgG1 κ chimeric antibody, targeting to human GPC3. Anti-GPC3 Antibody (YP7) reacts with the C-lobe of cell surface-associated glypican-3 (GPC3). Anti-GPC3 Antibody (YP7) can be used for the research of cancer, such as hepatocellular carcinoma (HCC) .
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Cat. No.: HY-17552R
CAS No.: 28319-77-9
Synonyms: Choline Alfoscerate (Standard); Alpha-GpC (Standard); L-α-GpC (Standard)
sn-Glycero-3-phosphocholine (Standard) is the analytical standard of sn-Glycero-3-phosphocholine. This product is intended for research and analytical applications. sn-Glycero-3-phosphocholine (Choline Alfoscerate) is a precursor in the biosynthesis of brain phospholipids and increases the bioavailability of choline in nervous tissue. sn-Glycero-3-phosphocholine (Choline Alfoscerate) has significant effects on cognitive function with a good safety profile and tolerability, and is effective in the treatment of Alzheimer's disease and dementia[1][2].
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Cat. No.: HY-P990842

Target:  

Glycoprotein VI

Research Areas:  

Cancer

Anti-GPC-2 Antibody (CT3) is a kind of mouse IgG1 κ chimeric antibody, targeting to human GPC-2. Anti-GPC-2 Antibody (CT3) reacts with tumor-associated exons 3 and 10 of glypicans-2 (GPC2). Anti-GPC-2 Antibody (CT3) can be used for the research of cancer, such as neuroblastoma .
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Cat. No.: HY-153838A
Synonyms: ODN 2395 Control sodium
Research Areas:  

Inflammation/Immunology

ODN 5328 (ODN 2395 Control) sodium can be used as a sequence control for C-class ODN 2395. ODN 5328 sodium shares the sequence with ODN 2395 but contain GpC dinucleotides instead of the CpG motifs.
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Cat. No.: HY-E70210
Synonyms: GpC
Target:  

DNA Methyltransferase

Research Areas:  

Cancer

GpC Methyltransferase (GpC) is a DNA methylating enzyme. GpC Methyltransferase methylates cytosines in GpC dinucleotides in non-nucleosomal DNA in vitro .
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Cat. No.: HY-P11281
CAS No.: 3063714-39-3
Target:  

Peptides

Research Areas:  

Inflammation/Immunology

GYGGGP(GPP)5GFOGER(GPP)5GPC is a type I collagen mimic that can bind to integrins and modify hydrogels .
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Cat. No.: HY-P11281A
Target:  

Peptides

Research Areas:  

Inflammation/Immunology

GYGGGP(GPP)5GFOGER(GPP)5GPC TFA is a type I collagen mimic that can bind to integrins and modify hydrogels .
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Cat. No.: HY-RS05626
Research Areas:  

Others

GPC1 Human Pre-designed siRNA Set A contains three designed siRNAs for GPC1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-153838
CAS No.: 500239-51-0
Synonyms: ODN 2395 Control
Research Areas:  

Inflammation/Immunology

ODN 5328 (ODN 2395 Control) can be used as a sequence control for C-class ODN 2395. ODN 5328 shares the sequence with ODN 2395 but contain GpC dinucleotides instead of the CpG motifs.
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Cat. No.: HY-17552S
CAS No.: 2260669-07-4
Synonyms: Choline Alfoscerate-d9; Alpha-GpC-d9; L-α-GpC-d9
sn-Glycero-3-phosphocholine-d9 is the deuterium labeled sn-Glycero-3-phosphocholine. sn-Glycero-3-phosphocholine (Choline Alfoscerate) is a precursor in the biosynthesis of brain phospholipids and increases the bioavailability of choline in nervous tissue. sn-Glycero-3-phosphocholine (Choline Alfoscerate) has significant effects on cognitive function with a good safety profile and tolerability, and is effective in the treatment of Alzheimer's disease and dementia .
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Cat. No.: HY-RS05629
Research Areas:  

Others

GPC4 Human Pre-designed siRNA Set A contains three designed siRNAs for GPC4 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-P991448

Target:  

Glycoprotein VI

Research Areas:  

Cancer

MDX-1414 is a human IgG1 monoclonal antibody (mAb) targeting GPC3. MDX-1414 has antitumor activity in the HepG2 xenograft model. MDX-1414 can be used in liver cancer research. Recommended isotype control: Human IgG1 kappa, Isotype Control (HY-P99001) .
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