28319-77-9
Chemical Structure
sn-Glycero-3-phosphocholine
Synonym(s): Choline Alfoscerate; Alpha-GPC; L-α-GPC
- CAS. Nr.: 28319-77-9
- Formula:C8H20NO6P
- Molecular Weight:257.22
IUPAC Name: (R)-2,3-dihydroxypropyl (2-(trimethylammonio)ethyl) phosphate
InChIKey: SUHOQUVVVLNYQR-MRVPVSSYSA-N
SMILES: O=P(OCC[N+](C)(C)C)(OC[C@H](O)CO)[O-]
Biological Activity: sn-Glycero-3-phosphocholine (Choline Alfoscerate) is a precursor in the biosynthesis of brain phospholipids and increases the bioavailability of choline in nervous tissue. sn-Glycero-3-phosphocholine (Choline Alfoscerate) has significant effects on cognitive function with a good safety profile and tolerability, and is effective in the treatment of Alzheimer's disease and dementia[1][2].
| Art. -Nr. | Produktname | Reinheit | Beschreibung | Pricing | |||||||||||||||||||
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sn-Glycero-3-phosphocholine | 98.0% | sn-Glycero-3-phosphocholine (Choline Alfoscerate) is a precursor in the biosynthesis of brain phospholipids and increases the bioavailability of choline in nervous tissue. sn-Glycero-3-phosphocholine (Choline Alfoscerate) has significant effects on cognitive function with a good safety profile and tolerability, and is effective in the treatment of Alzheimer's disease and dementia. | ||||||||||||||||||||
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sn-Glycero-3-phosphocholine (Standard) | 99.71% | sn-Glycero-3-phosphocholine (Standard) is the analytical standard of sn-Glycero-3-phosphocholine. This product is intended for research and analytical applications. sn-Glycero-3-phosphocholine (Choline Alfoscerate) is a precursor in the biosynthesis of brain phospholipids and increases the bioavailability of choline in nervous tissue. sn-Glycero-3-phosphocholine (Choline Alfoscerate) has significant effects on cognitive function with a good safety profile and tolerability, and is effective in the treatment of Alzheimer's disease and dementia. | ||||||||||||||||||||
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sn-Glycero-3-phosphocholine-d9 | 98.0% | sn-Glycero-3-phosphocholine-d9 is the deuterium labeled sn-Glycero-3-phosphocholine. sn-Glycero-3-phosphocholine (Choline Alfoscerate) is a precursor in the biosynthesis of brain phospholipids and increases the bioavailability of choline in nervous tissue. sn-Glycero-3-phosphocholine (Choline Alfoscerate) has significant effects on cognitive function with a good safety profile and tolerability, and is effective in the treatment of Alzheimer's disease and dementia. | ||||||||||||||||||||
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Similarity Score 1.00
HY-W096638Glycerylphosphorylcholine -
Similarity Score 1.00
HY-W096638AGlycerophosphocholine -
Similarity Score 0.74
HY-1576421-Hexanoyl-2-hydroxy-sn-glycero-3-phosphocholine -
Similarity Score 0.73
HY-1576441-Heptanoyl-2-hydroxy-sn-glycero-3-phosphocholine -
Similarity Score 0.72
HY-W1105512-Methacryloyloxyethyl phosphorylcholine -
Similarity Score 0.70
HY-W011249Phosphorylcholine chloride calcium salt tetrahydrate -
Similarity Score 0.70
HY-W129790N-Decylphosphorylcholine, 98% -
Similarity Score 0.70
HY-W7253271,2-Dipropionyl-sn-glycero-3-phosphocholine -
Similarity Score 0.69
HY-116013Dodecylphosphocholine -
Explore the MedChemAI to find more analogs
References
- [1]. Lee SH, et al. Late treatment with choline alfoscerate (l-alpha glycerylphosphorylcholine, α-GPC) increases hippocampal neurogenesis and provides protection against seizure-induced neuronal death and cognitive impairment. Brain Res. 2017 Jan 1;1654(Pt A):66-76. [Content Brief]
- [2]. Traini E, et al. Choline alphoscerate (alpha-glyceryl-phosphoryl-choline) an old choline- containing phospholipidwith a still interesting profile as cognition enhancing agent. Curr Alzheimer Res. 2013 Dec;10(10):1070-9. [Content Brief]
