Anti-GPC-2 Antibody (CT3)
Based on 1 Customer Validation
Anti-GPC-2 Antibody (CT3) is a kind of mouse IgG1 κ chimeric antibody, targeting to human GPC-2. Anti-GPC-2 Antibody (CT3) reacts with tumor-associated exons 3 and 10 of glypicans-2 (GPC2). Anti-GPC-2 Antibody (CT3) can be used for the research of cancer, such as neuroblastoma.
For research use only. We do not sell to patients.
- Purity: 95%
- Molecular Weight:150 kDa
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Mouse IgG1 kappa
Human
GPC-2
Anti-GPC-2 Antibody (CT3) (1 μg/mL) binds to tumor-associated exons 3 and 10 of GPC2[1].
Anti-GPC-2 Antibody (CT3) (CAR T cells harboring the single-chain variable fragment (scFv) of the CT3) (24 h) kills nearly 70% of GPC2-overexpressing A431 and IMR5 cells[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Anti-GPC-2 Antibody (CT3) (CAR T cells harboring the single-chain variable fragment (scFv) of the CT3) (2 M, i.v.) regresses tumor and prolongs survival in NBEB tumor NSG mice[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Animal Model:IMR5 tumor mice (5-week, female, NSG mice)[1]
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Dosage:10 M (CAR T cells harboring the single-chain variable fragment (scFv) of the CT3)
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Administration:Intravenously injection
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Result:Led to a reduction in tumor size and suppressed tumor growth.
Prolonged survival of mice.
Unconjugated
The product can be reconstituted/diluted with sterile PBS or saline.
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Product Image
Immunohistochemistry (paraffin); Flow cytometry; ELISA; Western blot
Chemical Information
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Appearance Liquid
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Molecular Weight 150 kDa
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Color Colorless to light yellow
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SMILES
[Anti-GPC-2 Antibody (CT3)]
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Formulation
Please refer to the lot-specific COA for specific buffer information.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
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Data Sheet (259 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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Inhibitory Antibodies User Guide (603 KB)
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Anti-GPC-2 Antibody (CT3) Related Classifications
HY-P990842 Related Classifications
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