DOTA-GPC3 targeting peptide 2
Based on 1 Customer Validation
DOTA-GPC3 targeting peptide 2 (Sequence 30) is a RDC peptide targeting GPC3, with Kd of 0.3 nM. DOTA-GPC3 targeting peptide 2 is composed of DOTA and GPC3 targeting peptide 2. DOTA-GPC3 targeting peptide 2 can be labeled with radioactive elements.
For research use only. We do not sell to patients.
- Purity: 98.83%
- CAS No.: 3066439-94-6
- Formula: C107H145N21O29S
- Molecular Weight:2221.48
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Storage:
-20°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
All Radionuclide-Drug Conjugates (RDCs) Isoforms
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Biological Activity
DOTA-GPC3 targeting peptide 2 is used to achieve high affinity and high selectivity in binding to the GPC3 protein. GPC3 is an overexpressed tumor-associated antigen in various solid tumors (especially hepatocellular carcinoma), and it is an important drug target[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 3066439-94-6
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Appearance Solid
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Molecular Weight 2221.48
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Formula C107H145N21O29S
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Color White to off-white
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
-20°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Solvent & Solubility
DMSO : ≥ 100 mg/mL (45.02 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
* "≥" means soluble, but saturation unknown.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (277 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 0.4502 mL | 2.2508 mL | 4.5015 mL | 11.2538 mL |
| 5 mM | 0.0900 mL | 0.4502 mL | 0.9003 mL | 2.2508 mL | |
| 10 mM | 0.0450 mL | 0.2251 mL | 0.4502 mL | 1.1254 mL | |
| 15 mM | 0.0300 mL | 0.1501 mL | 0.3001 mL | 0.7503 mL | |
| 20 mM | 0.0225 mL | 0.1125 mL | 0.2251 mL | 0.5627 mL | |
| 25 mM | 0.0180 mL | 0.0900 mL | 0.1801 mL | 0.4502 mL | |
| 30 mM | 0.0150 mL | 0.0750 mL | 0.1501 mL | 0.3751 mL | |
| 40 mM | 0.0113 mL | 0.0563 mL | 0.1125 mL | 0.2813 mL |
DOTA-GPC3 targeting peptide 2 Related Classifications
HY-W1124925 Related Classifications
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