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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
11 Results for "
HES-1
" in MedChemExpress (MCE) Product Catalog:
Products (11)
11 Results for "HES-1" in MCE Product Catalog:
1
1 Cited Publications
JI051 is a stabilizer for the Hes1-PHB2 interaction. JI051 interacts with a cancer-associated protein chaperone prohibitin 2 (PHB2), induces cell-cycle arrest by inhibiting the Notch downstream effector gene Hes1. Anti-cancer activity [1].
1
1 Cited Publications
Cat. No.: HY-RS06134
Target:
Research Areas:
HES1 Human Pre-designed siRNA Set A contains three designed siRNAs for HES1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
1
1 Cited Publications
Cat. No.: HY-P80155
Synonyms: bHLHb39 antibody;
C-HAIRY1 antibody;
Class B basic helix-loop-helix protein 39 antibody;
FLJ20408 antibody;
Hairy and enhancer of split 1 antibody;
Hairy homolog (Drosophila) antibody;
Hairy homolog antibody;
Hairy like antibody;
Hairy, Drosophila, homolog of antibody;
Hairy-like protein antibody;
HAIRY1 antibody;
HES-1 antibody;
HES1_HUMAN antibody;
HHL antibody;
HL antibody;
HRY antibody;
MGC129109 antibody;
OTTHUMP00000209031 antibody;
RHL antibody;
Transcription factor HES-1 antibody
Cat. No.: HY-N2740
CAS No.: 221257-06-3
Target:
Cat. No.: HY-124484
CAS No.: 2234271-86-2
JI130 (JI051 derivative ) is a stabilizer for the Hes1-PHB2 interaction. JI130 inhibits the ability of Hes1 to repress transcription. JI130 significantly reduces the tumor growth in a murine pancreatic tumor model and has the potential for managing pancreatic cancer [1].
Cat. No.: HY-N3393
CAS No.: 221289-31-2
Target:
Cat. No.: HY-RS17070
Target:
Research Areas:
Hes1 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Hes1 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS23514
Target:
Research Areas:
Hes1 Rat Pre-designed siRNA Set A contains three designed siRNAs for Hes1 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-181975
CAS No.: 956181-19-4
ATOX1-IN-1 is an inhibitor of ATOX1 (a copper chaperone protein) with a Kd value of 12.5 μM. ATOX1-IN-1 induces intracellular copper accumulation, increases the level of DNA methylation in the NOTCH1 promoter region, and inhibits the NOTCH1/HES1 signaling pathway. ATOX1-IN-1 enhances the sensitivity of hepatocellular carcinoma cells to Cisplatin (HY-17394). ATOX1-IN-1 can be used in hepatocellular carcinoma-related research [1].
Cat. No.: HY-N13201
CAS No.: 66583-59-3
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
