1 Result for "

HY-101005

" in MedChemExpress (MCE) Product Catalog:
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1 Results for "HY-101005" in MCE Product Catalog:

Cat. No.: HY-101005
CAS No.: 16503-22-3
Synonyms: Nα-MetHYlhistamine diHYdrochloride
Research Areas:  

Infection

N-Methylhistamine dihydrochloride (Nα-Methylhistamine dihydrochloride) is a non-selective Histamine receptor agonist. N-Methylhistamine dihydrochloride activates histamine H1, H2 and H3 receptors; it stimulates central H1 receptors by activating sympathetic α and β adrenergic receptors to inhibit intestinal transit, exerts dose-dependent inhibition on intestinal transit, reduces histamine turnover in mouse brains, and increases gastric acid secretion without altering plasma gastrin concentrations. N-Methylhistamine dihydrochloride produces a pH-dependent, voltage-independent potentiating effect on acid-sensing ion channel 1a, and shows no significant activity toward homologous ASIC2a channels. N-Methylhistamine dihydrochloride can be used in studies related to Helicobacter pylori infection .
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