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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
52 Results for "
Hepcidin
" in MedChemExpress (MCE) Product Catalog:
Products (52)
52 Results for "Hepcidin" in MCE Product Catalog:
64
64 Publications Verification
Synonyms: FG-4592
Roxadustat is an orally active hypoxia-inducible factor prolyl-hydroxylase (PHD) inhibitor (HIF-PHI) that promotes erythropoiesis through increasing endogenous erythropoietin, improving iron regulation, and reducing hepcidin .
6
6 Cited Publications
Referencia número: HY-112220
No. CAS: 2095668-10-1
Target:
Áreas de investigación:
VIT-2763, an oral ferroportin inhibitor, inhibits hepcidin binding to ferroportin and blocks iron efflux. VIT-2763 has the potential in the treatment of β-thalassemia .
2
2 Cited Publications
Synonyms: GDP disodium salt
2
2 Cited Publications
Synonyms: GDP sodium, Type I, 96% (HPLC)
2
2 Cited Publications
Referencia número: HY-P4373A
Áreas de investigación:
1
Target:
Áreas de investigación:
1
1 Cited Publications
Referencia número: HY-P70400
Pureza: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: HAMP; Liver-Expressed Antimicrobial Peptide 1; Hepcidin Antimicrobial Peptide; Putative Liver Tumor Regressor; LEAP1; Hepcidin; HEPC; PLTR; LEAP-1; Hepcidin Preproprotein; HFE2B
1
1 Cited Publications
Referencia número: HY-P700634
Pureza: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: HAMP; Liver-Expressed Antimicrobial Peptide 1; Hepcidin Antimicrobial Peptide; Putative Liver Tumor Regressor; LEAP1; Hepcidin; HEPC; PLTR; LEAP-1; Hepcidin Preproprotein; HFE2B
Referencia número: HY-P10272
No. CAS: 1628323-80-7
Synonyms: PTG-300
Target:
Áreas de investigación:
Target:
Áreas de investigación:
Hepcidin antagonist-1 (example 104) is a potent hepcidin (hepcidine) antagonist with an IC50<50 μM. Hepcidin antagonist-1 can be used for researching iron metabolism disorders, such as anemias .
Synonyms: INCB-000928; NBU-928
Target:
Áreas de investigación:
Zilurgisertib (INCB-000928; NBU-928) is a selective ALK2 inhibitor with an IC50 value of 15 nM. Zilurgisertib inhibits SMAD1/5 phosphorylation with an IC50 value of 63 nM. Zilurgisertib inhibits hepcidin production and improve anemia. Zilurgisertib can be used in melanoma research .
Referencia número: HY-P3494
No. CAS: 1356390-47-0
Áreas de investigación:
Referencia número: HY-177662
No. CAS: 2273007-95-5
Synonyms: IONIS-TMPRSS6-Lrx; ISIS 702843
Target:
Áreas de investigación:
Sapablursen, an antisense oligonucleotide, is designed to reduce the production of TMPRSS6 resulting in increased expression of hepcidin, which is the key regulator of iron homeostasis. Sapablursen can be used in the research of blood diseases such as pol
Referencia número: HY-P4373
No. CAS: 1676104-75-8
Áreas de investigación:
Referencia número: HY-P990617
Áreas de investigación:
Referencia número: HY-113066S1
Synonyms: GDP-13C10 dilithium
Referencia número: HY-147278
No. CAS: 2646704-10-9
Synonyms: Divesiran; SLN124
Áreas de investigación:
Manusiran (Divesiran) is a GalNac-siRNA targeting liver and transmembrane serine protease 6 (Serine protease 6). Manusiran increases hepatic Hepcidin synthesis and plasma levels by silencing TMPRSS6, a negative regulator of hepcidin production, and limits the availability of iron required for erythropoiesis. Combined use of Manusiran with Deferiprone (HY-B0568) reduces ineffective erythropoiesis and hepatic iron overload in a mouse model of β-thalassemia. Manusiran can be used for research on polycythemia vera, type 1 hereditary hemochromatosis, and β-thalassemia .
Referencia número: HY-113066S
Pureza: 98.20%
Synonyms: GDP-15N5 dilithium
Referencia número: HY-113066AR
No. CAS: 7415-69-2
Synonyms: GDP disodium salt (Standard)
Category:
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
