37 Results for "

Highly conserved

" in MedChemExpress (MCE) Product Catalog:
Products (37)

37 Results for "Highly conserved" in MCE Product Catalog:

4
4 Cited Publications
Cat. No.: HY-P0002
CAS No.: 24305-27-9
Synonyms: Thyrotropin-releasing-hormone; TRH
Protirelin is a highly conserved neuropeptide that exerts the hormonal control of thyroid-stimulating hormone (TSH) levels as well as neuromodulatory functions.
loading...
    loading...
4
4 Cited Publications
Cat. No.: HY-163002
CAS No.: 951945-67-8
Target:  

Ferroptosis

Research Areas:  

Cancer

viFSP1 is a species-independent FSP1 inhibitor. viFSP1 directly inhibits FSP1 by targeting the highly conserved NAD(P)H binding pocket of FSP1. viFSP1 can induce Ferroptosis in FSP1-dependent cells. viFSP1 can be used in renal and breast cancer research .
loading...
    loading...
4
4 Cited Publications
Cat. No.: HY-P0002A
CAS No.: 120876-23-5
Synonyms: Thyrotropin-releasing-hormone acetate; TRH acetate
Protirelin Acetate is a highly conserved neuropeptide that exerts the hormonal control of thyroid-stimulating hormone (TSH) levels as well as neuromodulatory functions.
loading...
    loading...
1
1 Cited Publications
Cat. No.: HY-P1852
CAS No.: 277302-47-3
Target:  

Adenylate Cyclase PTHR

Research Areas:  

Neurological Disease

TIP 39, Tuberoinfundibular Neuropeptide is an endogenous PTH2 receptor agonist and antihypertensive agent. TIP 39, Tuberoinfundibular Neuropeptide selectively activates the PTH2 receptor with no activity on the PTH1 receptor, stimulates cAMP production, activates adenylate cyclase, and elevates intracellular calcium levels via mobilization from intracellular stores. TIP 39, Tuberoinfundibular Neuropeptide is highly conserved in humans, mice, and rats. TIP 39, Tuberoinfundibular Neuropeptide is applicable to research related to nociception and inflammation-induced pain .
loading...
    loading...
Cat. No.: HY-W004305
CAS No.: 629-80-1
Synonyms: Palmitaldehyde
Hexadecanal (Palmitaldehyde) , a volatile long-chain aliphatic aldehyde, is emitted from human feces, skin, and breath. The receptor for hexadecanal(OR37B) is highly conserved across mammals. Hexadecanal may exert its effects by modulating functional connectivity between the brain substrates of social appraisal and the brain substrates of aggressive execution. Also, Hexadecanal is confirmed to be highly deterrent to the ant Lasius niger. Hexadecanal is promising for the research of startle responses and aggression
loading...
    loading...
Cat. No.: HY-P0230
CAS No.: 1613225-53-8
Target:  

Antibiotic Bacterial

Research Areas:  

Infection

Teixobactin is a potent antibiotic. Teixobactin shows antibacterial activity for gram-negative bacteria. Teixobactin inhibits cell wall synthesis by binding to a highly conserved motif of lipid II and lipid III .
loading...
    loading...
Cat. No.: HY-149048
CAS No.: 9025-54-1
Synonyms: SAHH; AHCY
Adenosylhomocysteinase (SAHH; AHCY) is a highly conserved enzyme. Adenosylhomocysteinase reversible catalyzes S-adenosylhomocysteine (SAH) to adenosine and L-homocysteine. The serum exosomal Adenosylhomocysteinase level can be used as a prognostic biomarker in HBV-LC patients .
loading...
    loading...
Cat. No.: HY-P3051
CAS No.: 99273-04-8
Target:  

Reverse Transcriptase

Research Areas:  

Inflammation/Immunology

CKS-17 is a synthetic retroviral envelope peptide. CKS-17 has the highly conserved amino acid sequences occurring within the transmembrane envelope protein of many animal and human retroviruses. CKS-17 acts as an immunomodulatory epitope and exhibits suppressive properties for numerous immune functions .
loading...
    loading...
Cat. No.: HY-P99637
CAS No.: 1807954-17-1
Synonyms: MHAA4549A; RG7745

Target:  

Influenza Virus

Research Areas:  

Infection

Gedivumab (MHAA4549A; RG7745) is a human monoclonal antibody that targets influenza A virus (IAV) with high specificity and binds to the highly conserved stem region of the IAV haemagglutinin protein, thereby preventing haemagglutinin maturation and blocking haemagglutinin-mediated membrane fusion in the intranucleosome. Gedivumab can be used in IAV infection disease studies .
loading...
    loading...
Cat. No.: HY-N6978
CAS No.: 1086696-26-5
Synonyms: Ascaroside C3
Ascr#5 is a highly conserved ascaroside isolated from Caenorhabditis elegans.
loading...
    loading...
Cat. No.: HY-P99727
CAS No.: 2419087-89-9
Synonyms: CTB012

Target:  

RABV

Research Areas:  

Infection

Mazorelvimab (CTB012) is an anti-rabies humanized IgG1κ monoclonal antibody that binds to the non-overlapping epitopes on the rabies virus (RABV) glycoprotein. Mazorelvimab binds to highly discontinuous conserved residues that are not in or near antigenic site III. Mezagitamab has potential application in the prevention of rabies .
loading...
    loading...
Cat. No.: HY-146074
CAS No.: 423128-55-6
Purity:  99.63%
Target:  

Proton Pump

Research Areas:  

Cancer

RUVBL1/2 ATPase-IN-1 (compound 18) is a potent and selective inhibitor of RUVBL1/2 ATPase with IC50 values of 6.0 and 7.7 μM, respectively. RUVBL1 and RUVBL2 are highly conserved AAA ATPases (ATPases Associated with various cellular Activities) and highly relevant to the progression of cancer. RUVBL1/2 ATPase-IN-1 has the potential for the research of cancer diseases .
loading...
    loading...
Cat. No.: HY-P2918
CAS No.: 9001-41-6
Synonyms: GPI; Phosphoglucose Isomerase
Target:  

Endogenous Metabolite

Research Areas:  

Metabolic Disease Cancer

Phosphoglucose Isomerase, Rabbit muscle (GPI), i.e., phosphoglucose isomerase/phosphoglucoisomerase (PGI) or phosphohexose isomerase (PHI), is often used in biochemical studies. Glucose 6-phosphate isomeras is a highly conserved glycolytic and dimeric enzyme. Glucose 6-phosphate isomeras catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate .
loading...
    loading...
Cat. No.: HY-P1837
CAS No.: 186302-15-8
Target:  

Influenza Virus HSV

Research Areas:  

Infection

Influenza HA (518-526) is an H-2d-restricted CTL epitope derived from influenza virus hemagglutinin. Influenza HA (518-526) is highly conserved across various H5N1, some H9N2, and H1N1 strains. Influenza HA (518-526) binds to the mouse MHC class I allele K d to form a complex, which is then recognized by specific CD8 + T cells. Influenza HA (518-526) is an immunodominant epitope in influenza-infected BALB/c mice, and it stimulates CD8 + T cells to secrete IFN-γ to induce a robust immune response. Currently, Influenza HA (518-526) is widely used in research related to respiratory syncytial virus (RSV), influenza virus, and H5N1 influenza .
loading...
    loading...
Cat. No.: HY-E70625
Target:  

Casein Kinase

Research Areas:  

Cancer

Casein Kinase 2 (CK2) is a serine/threonine protein kinase that is highly conserved among eukaryotes and has roles in many different cellular processes, such as cell survival, cell cycle regulation, cell polarity, stress responses, transcription and translation .
loading...
    loading...
Cat. No.: HY-P3035
CAS No.: 122929-08-2
Corazonin is a highly conserved neuropeptide hormone of wide-spread occurrence in insects, serves a central regulator of caste identity and behavior in social insects. Corazonin is also preferentially expressed in workers and/or foragers from other social insect species .
loading...
    loading...
Cat. No.: HY-P0303
CAS No.: 309247-84-5
Crustacean cardioactive peptide, free acid is a highly conserved, amidated cyclic nonapeptide, first isolated from the pericardial organs of the shore crab Carcinus maenas, where it has a role in regulating heartbeat; Crustacean cardioactive peptide, free acid also modulates the neuronal activity in other arthropods.
loading...
    loading...
Cat. No.: HY-P99608
CAS No.: 569658-80-6

Target:  

HBV

Research Areas:  

Infection

Exbivirumab is a monoclonal antibody directed against highly conserved HBsAg epitopes. Exbivirumab enhances the antiviral activity of hepatitis B immunoglobulin (HBIG). Exbivirumab combined with Libivirumab (HY-P99703) decreases circulating HBsAg and hepatitis B virus (HBV) DNA levels in a chronically infected chimpanzee. Exbivirumab can be used for HBV re-infection in liver transplant .
loading...
    loading...
Cat. No.: HY-P2918A
CAS No.: 9001-41-6
Target:  

Endogenous Metabolite

Research Areas:  

Metabolic Disease

Phosphoglucose isomerase, bacillus stearothermophilus is a highly conserved glycolytic and dimeric enzyme. Phosphoglucose isomerase, bacillus stearothermophilus catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate .
loading...
    loading...
Cat. No.: HY-P2918B
CAS No.: 9001-41-6
Target:  

Endogenous Metabolite

Research Areas:  

Metabolic Disease

Phosphoglucose isomerase, bacillus stearothermophilus is a highly conserved glycolytic and dimeric enzyme. Phosphoglucose isomerase, bacillus stearothermophilus catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate .
loading...
    loading...