186302-15-8
Chemical Structure
Influenza HA (518-526)
- CAS No.: 186302-15-8
- Formula:C42H69N9O15
- Molecular Weight:940.05
IUPAC Name: L-isoleucyl-L-tyrosyl-L-seryl-L-threonyl-L-valyl-L-alanyl-L-seryl-L-seryl-L-leucine
InChIKey: HPOMZIOCDIYOTE-JRCYYVIGSA-N
SMILES: CC(C)C[C@@H](C(O)=O)NC([C@H](CO)NC([C@H](CO)NC([C@H](C)NC([C@H](C(C)C)NC([C@H]([C@H](O)C)NC([C@H](CO)NC([C@H](CC1=CC=C(O)C=C1)NC([C@H]([C@@H](C)CC)N)=O)=O)=O)=O)=O)=O)=O)=O
Biological Activity: Influenza HA (518-526) is an H-2d-restricted CTL epitope derived from influenza virus hemagglutinin. Influenza HA (518-526) is highly conserved across various H5N1, some H9N2, and H1N1 strains. Influenza HA (518-526) binds to the mouse MHC class I allele Kd to form a complex, which is then recognized by specific CD8+ T cells. Influenza HA (518-526) is an immunodominant epitope in influenza-infected BALB/c mice, and it stimulates CD8+ T cells to secrete IFN-γ to induce a robust immune response. Currently, Influenza HA (518-526) is widely used in research related to respiratory syncytial virus (RSV), influenza virus, and H5N1 influenza[1][2][3].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Influenza HA (518-526) | 98.28% | Influenza HA (518-526) is an H-2d-restricted CTL epitope derived from influenza virus hemagglutinin. Influenza HA (518-526) is highly conserved across various H5N1, some H9N2, and H1N1 strains. Influenza HA (518-526) binds to the mouse MHC class I allele Kd to form a complex, which is then recognized by specific CD8+ T cells. Influenza HA (518-526) is an immunodominant epitope in influenza-infected BALB/c mice, and it stimulates CD8+ T cells to secrete IFN-γ to induce a robust immune response. Currently, Influenza HA (518-526) is widely used in research related to respiratory syncytial virus (RSV), influenza virus, and H5N1 influenza. | ||||||||||||||||||||
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References
- [1]. De Baets S, et al. Recombinant influenza virus carrying the respiratory syncytial virus (RSV) F85-93 CTL epitope reduces RSV replication in mice. J Virol. 2013;87(6):3314-3323. [Content Brief]
- [2]. Jiang J, et al. Enhancement of virus-specific expansion of transgenic CD8 T cells in aged mice by dendritic cells. Mech Ageing Dev. 2010;131(9):580-583. [Content Brief]
- [3]. Hoelscher MA, et al. Development of adenoviral-vector-based pandemic influenza vaccine against antigenically distinct human H5N1 strains in mice. Lancet. 2006;367(9509):475-481. [Content Brief]
