951945-67-8
951945-67-8
Chemical Structure
viFSP1
- CAS No.: 951945-67-8
- Formula:C16H17N3O3S
- Molecular Weight:331.39
InChIKey: OUJMVDXLUWMMEC-UHFFFAOYSA-N
SMILES: O=C1C(C2=NC(C)=CS2)=C(N(C1)C3=CC=C(C=C3OC)OC)N
Biological Activity: viFSP1 is a species-independent FSP1 inhibitor. viFSP1 directly inhibits FSP1 by targeting the highly conserved NAD(P)H binding pocket of FSP1. viFSP1 can induce Ferroptosis in FSP1-dependent cells. viFSP1 can be used in renal and breast cancer research[1][2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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viFSP1 | 99.50% | viFSP1 is a species-independent FSP1 inhibitor. viFSP1 directly inhibits FSP1 by targeting the highly conserved NAD(P)H binding pocket of FSP1. viFSP1 can induce Ferroptosis in FSP1-dependent cells. viFSP1 can be used in renal and breast cancer research. | ||||||||||||||||||||
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References
- [1]. Nakamura T et al. Integrated chemical and genetic screens unveil FSP1 mechanisms of ferroptosis regulation. Nat Struct Mol Biol. 2023 Nov;30(11):1806-1815. [Content Brief]
- [2]. Chen X, et al. SENP3 sensitizes macrophages to ferroptosis via de-SUMOylation of FSP1. Redox Biol. 2024 Sep;75:103267. [Content Brief]
Keywords
