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Cat. No.: HY-P3035

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Corazonin

Corazonin is a highly conserved neuropeptide hormone of wide-spread occurrence in insects, serves a central regulator of caste identity and behavior in social insects. Corazonin is also preferentially expressed in workers and/or foragers from other social insect species.

For research use only. We do not sell to patients.

CAS No.: 122929-08-2
Formula: C₆₂H₈₃N₁₇O₁₉
Molecular Weight:1370.42

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Corazonin Chemical Structure

CAS No.: 122929-08-2

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- In Vitro
- In Vivo
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

Description

In Vitro

Corazonin is produced by lateral brain neurosecretory cells projecting to the corpora cardiaca-corpora allata complex and in neurons of the ventral nerve cord^[1].
Corazonin evokes inward currents in Xenopus oocytes with an EC₅₀ value of 200 pM and leads to luminescence response from CHO cells with an EC₅₀ value of 75 pM, respectively^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

In Vivo

Corazonin (5.4 ng/brain; injection; single dose) suppresses expression of vitellogenin in the brain and stimulates worker-like hunting behaviors, while inhibiting gamergate behaviors, such as dueling and egg deposition in transitioning Harpegnathos individuals^[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 122929-08-2
Molecular Weight 1370.42
Formula C₆₂H₈₃N₁₇O₁₉
Sequence Shortening

{Pyr}-TFQYSRGWTN-NH2
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (259 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Kim YJ, et al. Corazonin receptor signaling in ecdysis initiation. Proc Natl Acad Sci U S A. 2004 Apr 27;101(17):6704-9. [Content Brief]

[2]. Gospocic J, et al. The Neuropeptide Corazonin Controls Social Behavior and Caste Identity in Ants. Cell. 2017 Aug 10;170(4):748-759.e12. [Content Brief]

Calculators

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

100 mg

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